The Journal of the Royal Statistical Society (JRSS) is a prestigious academic journal published by the Royal Statistical Society (RSS) in the United Kingdom. It is divided into several series, with the most prominent being: 1. **Series A: Statistics in Society** - This series focuses on the application of statistical methods to social science and public policy, exploring how statistical analysis can inform societal decisions.
Security printing refers to the specialized processes and techniques used to produce documents and items that are resistant to forgery, counterfeiting, and unauthorized alteration. These items can include banknotes, passports, identity cards, stamps, product packaging, and high-value certificates, among others. Key features of security printing include: 1. **Specialized Inks**: Use of UV-reactive inks, color-shifting inks, or thermochromic inks that change color with temperature.
Baldwin's Rules refer to a set of guidelines or principles regarding the application of knowledge and the importance of mutual understanding and respect in communication, particularly in the context of academic discourse or professional environments. While there are various interpretations and applications of Baldwin's Rules depending on the field of study, the most commonly referenced set of principles is associated with the work of James Baldwin, an influential African American writer and social critic.
Chiral drugs are pharmaceutical compounds that possess chirality, meaning they exist in multiple forms that are mirror images of each other, known as enantiomers. This characteristic arises from the presence of a specific carbon atom (often referred to as a chiral center) that is bonded to four different substituents. Because of this asymmetry, two enantiomers can have significantly different biological activities, side effects, and pharmacokinetics.
The Cahn–Ingold–Prelog priority rules are a set of guidelines used to assign priority to substituents attached to a chiral center in organic molecules. These rules are crucial for determining the configuration (R or S) of chiral centers in stereochemistry. Here's a summary of how the rules work: 1. **Atomic Number**: Compare the atomic numbers of the atoms directly attached to the chiral center. The substituent with the higher atomic number takes precedence.
An epimer is a type of stereoisomer that differs from another compound in the configuration around just one specific stereogenic center (chiral center). This means that while the two compounds have the same molecular formula and may be very similar overall, they have different spatial arrangements of atoms at only one of their chiral centers. Epimers are particularly common in carbohydrate chemistry. For example, glucose and galactose are epimers because they differ at only one carbon atom (C4).
Chirality is a property of asymmetry important in several branches of science, particularly in chemistry, biology, and physics. An object or a molecule is considered chiral if it cannot be superimposed on its mirror image. This means that a chiral object has a distinct handedness, much like how left and right hands are mirror images of each other but cannot be aligned perfectly. In chemistry, chirality is most often discussed in the context of molecules.
Chirality-induced spin selectivity (CISS) is a physical phenomenon where chiral molecules exhibit a preference for spinning electrons in a certain direction. This effect is observed in systems that include chiral organic molecules, which are structures that cannot be superimposed on their mirror images, much like left and right hands. The key points about CISS are: 1. **Chirality**: Chiral molecules have non-superimposable mirror images.
Desymmetrization is a concept used in various fields, particularly in chemistry and mathematics, referring to the process of breaking symmetry in a system that possesses symmetrical properties. In chemistry, desymmetrization is often discussed in the context of synthetic organic chemistry and is related to the design and synthesis of chiral molecules. Chiral molecules are those that cannot be superimposed on their mirror images, and they often have important implications in pharmaceuticals and biological activity.
Diastereomers are a type of stereoisomer that are not mirror images of each other. They occur when a molecule has multiple stereocenters (chiral centers) and varies at one or more, but not all, of those centers. This leads to different spatial arrangements of the atoms in the molecule, resulting in distinct compounds with different physical and chemical properties. For example, consider a molecule with two chiral centers.
Homometric structures refer to a concept in geometry and topology that pertains to the idea that two or more shapes can have the same or indistinguishable measurements, such as lengths or angles, despite being different in form or arrangement. In other words, two structures are considered homometric if they can be transformed into one another through a series of isometries (like rotation, translation, or reflection) while maintaining the same metric properties.
Proline isomerization refers to the process by which the peptide bond involving the amino acid proline can exist in either a cis or trans configuration. This is particularly relevant in the context of protein structure and function, as the isomerization can influence protein folding, stability, and interactions. In epigenetics, proline isomerization can play a role in the regulation of chromatin structure and gene expression.
Enantiomeric excess (ee) is a measure of the purity of a chiral compound in terms of the proportion of one enantiomer relative to the other. Enantiomers are pairs of molecules that are non-superimposable mirror images of each other, and they often differ in their biological activity and properties.
The Fürst-Plattner Rule is a guideline used in mineral processing, particularly in the context of determining the viability of extracting metals from ore. It specifically relates to the extraction of silver from silver-bearing ores, although its principles can sometimes be applied to other metals as well. The rule suggests that the value of the metal that can be extracted must exceed the cost of recovering it, including expenses related to mining, milling, and refining the ore.
The ligand cone angle is a concept used in coordination chemistry to describe the spatial orientation of ligands around a central metal ion in a coordination complex. It refers to the geometric representation of how ligands are arranged and the degree to which they can approach and interact with the central metal atom.
Pseudorotation is a term used in chemistry and molecular physics to describe a specific type of conformational change in certain cyclic compounds, particularly in the context of five-membered rings or certain larger rings. It involves the movement of atoms within the molecule that allows the structure to rotate around a particular axis, leading to a change in the arrangement of atoms or groups attached to the ring without breaking any bonds.
The biosphere is the global sum of all ecosystems, representing the zone of life on Earth. It includes all living organisms, including plants, animals, and microorganisms, as well as the environments in which they interact. The biosphere is characterized by the interactions between these organisms and their physical surroundings, including the atmosphere (air), hydrosphere (water), and lithosphere (land).
The stereoelectronic effect refers to the influence of molecular geometry on electronic interactions and reactivity, particularly in the context of chemical bonding and reaction mechanisms. It describes how the spatial arrangement of atoms and the orientation of orbitals can affect the electronic properties of a molecule and, consequently, its reactivity. In essence, the stereoelectronic effect highlights the relationship between the arrangement of bonds in three-dimensional space and the electron distribution in molecular orbitals.
Syn and anti addition refer to the specific orientations of the addition of reactants across a double bond in organic molecules. These terms are especially important in the context of stereochemistry, the study of the three-dimensional arrangements of atoms within molecules. 1. **Syn Addition**: - In syn addition, the two substituents are added to the same side (or face) of the double bond.
Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 3. Visual Studio Code extension installation.Figure 4. Visual Studio Code extension tree navigation.Figure 5. Web editor. You can also edit articles on the Web editor without installing anything locally.Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.Video 4. OurBigBook Visual Studio Code extension editing and navigation demo. Source. - Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact





