The Chemical Shift Index (CSI) is a concept primarily used in the field of NMR (nuclear magnetic resonance) spectroscopy, particularly in the analysis and interpretation of protein structures and their dynamics. It is a way to evaluate the local environment of specific nuclei—usually protons (hydrogens)—in a molecule, and is derived from the chemical shifts observed in the NMR spectrum. The CSI is often utilized to provide insights into the secondary structure of proteins.

Protein chemical shift prediction refers to the computational method used to estimate the chemical shifts of nuclei in protein molecules, most commonly for proton (^1H), carbon (^13C), and nitrogen (^15N) isotopes. Chemical shifts are fundamental parameters in nuclear magnetic resonance (NMR) spectroscopy, a powerful technique for studying the structures and dynamics of proteins and other biomolecules.

Composed by Bo Ya for the guqin.

But there is an awesome guzheng adaptation which is perhaps better known in modern times, partly because it is not as long/slow. TODO origin.

The Database of Molecular Motions is a specialized resource that catalogs and provides access to information about the dynamic movements of molecules, primarily proteins, in various biological contexts. This database often contains detailed information about the conformational changes, interactions, and dynamics of biomolecules observed through experimental techniques such as X-ray crystallography, NMR spectroscopy, and molecular dynamics simulations.

The Journal of Biomedical Materials Research (JBMR) is a peer-reviewed scientific journal that focuses on the field of biomedical materials. It publishes research articles, reviews, and technical notes related to the design, application, and development of materials used in biomedical applications, including tissue engineering, drug delivery systems, implants, and other medical devices.

Like the U.S.' spring term.

He's a bit overly obsessed with polynomials for the taste of modern maths, but it's still fun.

Fast parallel proteolysis is a technique used in proteomics and protein analysis that allows for the rapid and efficient digestion of proteins into peptides using proteolytic enzymes. This method is particularly beneficial for mass spectrometry applications, as it enables the generation of peptide fragments that can be analyzed for protein identification and quantification. The term "fast parallel" refers to the ability to process multiple samples simultaneously and to do so in a shorter time frame compared to traditional proteolysis methods.

Fluorescence recovery after photobleaching (FRAP) is a quantitative imaging technique used primarily in cell biology to study the dynamics of fluorescently labeled molecules within live cells. The method provides insights into the movement and interactions of proteins, lipids, and other biomolecules in cellular membranes and structures.

A Frog galvanoscope is a historical scientific instrument used to detect electric currents. It was developed based on the observations of physiologist Luigi Galvani in the late 18th century, who discovered that the muscles of a frog's leg would contract when exposed to an electric current. The instrument typically consists of a frog's leg (often preserved) attached to a metallic frame.

Operated by a hand crank.

Gated drug delivery systems are advanced pharmaceutical technologies designed for the controlled release of therapeutic agents. These systems enhance the efficacy and safety of medications by regulating the release of drugs in response to specific environmental triggers. ### Key Features: 1. **Gating Mechanism**: The release of the drug is controlled by a "gate" that can open or close under certain conditions. Triggers may include changes in pH, temperature, light, or the presence of specific biomolecules (like enzymes).

Lipid polymorphism refers to the ability of lipids to adopt multiple structural forms or phases under different conditions, such as changes in temperature, hydration, or chemical environment. This phenomenon is significant in the study of biological membranes, drug delivery systems, and other applications where lipids play a crucial role.

The list of biophysically important macromolecular crystal structures typically includes a variety of key biomolecules, such as proteins, nucleic acids, and their complexes, that have been structurally characterized through X-ray crystallography or other crystallographic methods. Here are some categories and examples of such structures that are often regarded as significant in biophysics and structural biology: ### Proteins 1.

Hydrophobicity scales are numerical or graphical representations that quantify the hydrophobic (water-repelling) or hydrophilic (water-attracting) nature of amino acids or other molecules. These scales are valuable in biochemistry and molecular biology for understanding protein folding, interactions, and the behavior of biomolecules in aqueous environments. ### Key Points about Hydrophobicity Scales: 1. **Hydrophobicity Measurement**: The scales measure the tendency of a substance or amino acid to interact with water.

These are apparenty an important part of transcriptional regulation given the number of modifications they can undergo! Quite exciting.

The Journal of Cellular Plastics is a scientific publication that focuses on research and development related to cellular plastics, which are a category of materials characterized by their cellular structure and lightweight properties. These materials often exhibit beneficial qualities such as low density, thermal insulation, and sound absorption, making them useful in various applications including packaging, construction, automotive, and aerospace industries.