Run output is placed under out/:
Some of the output data is stored as .cpickle files. To observe those files, you need the original Python classes, and therefore you have to be inside Docker, from the host it won't work.
We can list all the plots that have been produced under out/ with
find -name '*.png'
Plots are also available in SVG and PDF formats, e.g.:
  • PNG: ./out/manual/plotOut/low_res_plots/massFractionSummary.png
  • SVG: ./out/manual/plotOut/svg_plots/massFractionSummary.svg The SVGs write text as polygons, see also: SVG fonts.
  • PDF: ./out/manual/plotOut/massFractionSummary.pdf
The output directory has a hierarchical structure of type:
./out/manual/wildtype_000000/000000/generation_000000/000000/
where:
  • wildtype_000000: variant conditions. wildtype is a human readable label, and 000000 is an index amongst the possible wildtype conditions. For example, we can have different simulations with different nutrients, or different DNA sequences. An example of this is shown at run variants.
  • 000000: initial random seed for the initial cell, likely fed to NumPy's np.random.seed
  • genereation_000000: this will increase with generations if we simulate multiple cells, which is supported by the model
  • 000000: this will presumably contain the cell index within a generation
We also understand that some of the top level directories contain summaries over all cells, e.g. the massFractionSummary.pdf plot exists at several levels of the hierarchy:
./out/manual/plotOut/massFractionSummary.pdf
./out/manual/wildtype_000000/plotOut/massFractionSummary.pdf
./out/manual/wildtype_000000/000000/plotOut/massFractionSummary.pdf
./out/manual/wildtype_000000/000000/generation_000000/000000/plotOut/massFractionSummary.pdf
Each of thoes four levels of plotOut is generated by a different one of the analysis scripts:
  • ./out/manual/plotOut: generated by python runscripts/manual/analysisVariant.py. Contains comparisons of different variant conditions. We confirm this by looking at the results of run variants.
  • ./out/manual/wildtype_000000/plotOut: generated by python runscripts/manual/analysisCohort.py --variant_index 0. TODO not sure how to differentiate between two different labels e.g. wildtype_000000 and somethingElse_000000. If -v is not given, a it just picks the first one alphabetically. TODO not sure how to automatically generate all of those plots without inspecting the directories.
  • ./out/manual/wildtype_000000/000000/plotOut: generated by python runscripts/manual/analysisMultigen.py --variant_index 0 --seed 0
  • ./out/manual/wildtype_000000/000000/generation_000000/000000/plotOut: generated by python runscripts/manual/analysisSingle.py --variant_index 0 --seed 0 --generation 0 --daughter 0. Contains information about a single specific cell.
Nobel disease by Ciro Santilli 40 Updated 2025-09-11
The Eighth Day of Creation has a related quote:
In a conversation a few weeks earlier at the faculty club of the Massachusetts Institute of Technology, a couple of biologists had speculated whether Pauling, whose recent popular book on the benefits to health and sanity of massive doses of vitamin C was stacked in display near the entrance of the M.I.T. bookstore, was showing signs of what one of the men called "old scientist's disease" - which they defined as what happens to great men when they grow beyond the psychological reach of the salutary system by which scientists blow the whistle on one another's mistakes.
Video 1.
The Nobel Prize Winners With Crazy Theories by Qxir
. Source.
This website used to allow embedding text messages with OP_RETURN, here's an archive from 2015: web.archive.org/web/20150718052659/http://eternitywall.it/
As of January 2024, it seems to read-only mode, where it simply indexes matching transactions that were made via other means: web.archive.org/web/20230929075331/https://eternitywall.it/
There were 3191 hits for the search term:
git grep '\bEW '
in our data starting with tx a3b3af21514bd79a4cbcac9916a8514636a72d813539192214542fd85247082e (2015-06-24):
EW Eternity wall is live
up to the last entry on tx 28820bc14cf2cfda58ecbc9ac6df3f41a1cb90f4246543f01ba42a5e9dac3cf8 (2023-06-15)
EW May our friendship endure, signed by hg, kty, wjj, and xyz.
no doubt initials of 4 Chinesepeople. A blood brother oath comes to mind, akin to the Oath of the Peach Garden. Will these four be the ones to take down the evil dictator Xi Jinping?
The very first message gives away the name of what we assume is a web-based upload system, "EW" being its advertisement signature added to every message.
Running bitcoin-cli:
bitcoin-core.cli getrawtransaction a3b3af21514bd79a4cbcac9916a8514636a72d813539192214542fd85247082e true
shows that the messages are encoded with OP_RETURN:
  "vout": [
    {
      "value": 0.00000000,
      "n": 0,
      "scriptPubKey": {
        "asm": "OP_RETURN 455720457465726e6974792077616c6c206973206c697665
Microbotics by Ciro Santilli 40 Updated 2025-07-16
Video 1.
10 TINY Micro Robots and Nano Drones by JUST AMAZING (2020)
Source.
Bibliography:
Exoticism by Ciro Santilli 40 Updated 2025-07-16
Video 1.
Emmenez-moi by Charles Aznavour (1968)
Source. The ultimate ode to exoticism.
The Godfather by Ciro Santilli 40 Updated 2025-07-16
www.youtube.com/playlist?list=PLVV0r6CmEsFzCodipONmNiROhYCUWyz_U interview with Walter Murch by Web of Stories. He worked on sound design for all The Godfather films, and tells some interesting details about it. He's just super nice in general otherwise. E.g.:
Break the meta by Ciro Santilli 40 Updated 2025-07-16
To break the meta means to find a new strategy that offers a significant advantage over the existing meta.
Video 1.
How One Man Changed the High Jump Forever by Olympics (2018)
Source. Dick Fosbury created and implemented the Fosbury Flop jump style in 1968.
Video 2.
Akiyo Noguchi asks the rules while climbing! | Beta Break Ep.1 by Albert Ok (2020)
Source. Happened at the 2015 IFSC Climbing World Cup during the Haiyang, China, bouldering event. The author has a playlist of such climbing meta breaks. In climbing, the meta is called "the beta". Climbing competitions are perhaps the sport in which the meta is broken the most often, since each stage is unique.
Video 3.
Lukas Hofer's Revolutionary Technique by IBU TV (2019)
Source. Lukas created a new technique to pack up his rifle during biathlon competitions.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 2.
    You can publish local OurBigBook lightweight markup files to either https://OurBigBook.com or as a static website
    .
    Figure 3.
    Visual Studio Code extension installation
    .
    Figure 4.
    Visual Studio Code extension tree navigation
    .
    Figure 5.
    Web editor
    . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
    Video 4.
    OurBigBook Visual Studio Code extension editing and navigation demo
    . Source.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact