Protein structure prediction is the process of determining the three-dimensional shape of a protein based on its amino acid sequence. Since proteins are essential biological molecules involved in countless cellular functions, understanding their structure is crucial for various applications in biochemistry, molecular biology, and medicine. Protein structure can be described at different levels: 1. **Primary Structure**: The linear sequence of amino acids in a polypeptide chain.
Structural genomics is a field of biological research that focuses on the three-dimensional structure of proteins and nucleic acids to better understand their functions and interactions. It combines structural biology, genomics, and bioinformatics to systematically study the structures of all or a significant portion of the proteins encoded by a given genome.
Discovery Investigations is typically associated with a range of services that pertain to private investigation, research, and intelligence gathering. However, since "Discovery Investigations" can refer to different entities or services depending on the context, it's important to clarify what specific aspect you are referring to.
Synthetic biology is an interdisciplinary field that combines principles from biology, engineering, and computer science to design and construct new biological parts, devices, and systems, or to re-engineer existing biological organisms for useful purposes. The aim of synthetic biology is to create innovative biological systems that can solve specific problems in areas such as medicine, agriculture, environmental sustainability, and biofuels.
"Toponome" is not a widely recognized term in common language, geography, or science up to my knowledge cutoff in October 2023. However, it might refer to various concepts depending on the context in which it's used, such as: 1. **Toponymy**: This is the study of place names (toponyms) and their origins, meanings, and use. It involves analyzing how geographic names reflect cultural, historical, and linguistic influences.
The Nussinov algorithm is a dynamic programming algorithm used for RNA secondary structure prediction. It specifically addresses the problem of finding the optimal folding of a given RNA sequence by maximizing the number of base pairs that can form under specific pairing rules.
Brown algae, belonging to the phylum Phaeophyta, are a diverse group of photosynthetic organisms primarily found in marine environments, particularly in colder waters. They are characterized by their brown or olive-green color, which is due to the presence of the pigment fucoxanthin, along with chlorophyll a and c. Brown algae vary in size, ranging from small filaments to large kelps that can grow to several meters in length.
UPGMA, or the Unweighted Pair Group Method with Arithmetic Mean, is a clustering method used in bioinformatics and other fields for constructing phylogenetic trees. It is a hierarchical clustering algorithm that builds a tree based on the similarity or distance between pairs of data points. Here’s a brief overview of how UPGMA works: 1. **Starting Point**: Begin with a distance matrix that represents the pairwise distances between each set of data points (such as species or genes).
Extracellular polymeric substances (EPS) are complex mixtures of high-molecular-weight substances produced by microorganisms, particularly bacteria and other forms of microbial communities. EPS are a crucial component of biofilms, which are structured communities of microorganisms attached to surfaces. Key characteristics of EPS include: 1. **Composition**: EPS is primarily composed of polysaccharides, proteins, nucleic acids, and lipids. The specific composition can vary significantly among different microbial species and environmental conditions.
Ichthyoplankton refers to the early life stages of fish that are found in the plankton community of marine and freshwater ecosystems. This group primarily includes fish eggs and larval fish, which drift in the water column and are crucial components of aquatic food webs. Ichthyoplankton plays an important role in the ecology of aquatic systems as they serve as prey for a variety of larger organisms, including other fish, invertebrates, and birds.
The Center for Microbial Oceanography: Research and Education (C-MORE) is a research and educational initiative that focuses on the study of microbial life in the ocean and its impact on marine ecosystems and global biogeochemical cycles. Established with the aim of advancing our understanding of the role that microbes play in oceanic processes, C-MORE conducts interdisciplinary research that combines microbiology, oceanography, and environmental science.
Marine microorganisms are tiny living organisms found in ocean and sea environments. They are typically microscopic in size and include a wide variety of life forms, such as bacteria, archaea, viruses, phytoplankton, and zooplankton. These microorganisms play crucial roles in marine ecosystems and are vital for the health of our planet. Here are some key aspects of marine microorganisms: 1. **Bacteria and Archaea**: These are prokaryotic microorganisms that thrive in diverse marine environments.
Zooplankton are a diverse group of small, often microscopic, animals that drift in ocean and freshwater environments. They are an essential component of aquatic ecosystems and serve as a critical link in the food web, primarily by feeding on phytoplankton (the microscopic plant-like organisms) and, in turn, serving as prey for larger animals, such as fish and whales.
SUPER HI-CAT (System for Ultra-High-Temperature Icing Conditions and Atmospheric Turbulence) is a research initiative aimed at studying and understanding the effects of icing and turbulence on aircraft and other vehicles. The project focuses on extreme climatic conditions that can pose safety risks to aviation, particularly during takeoff and landing phases.
Whale feces, often referred to as whale dung, is the excrement produced by whales. It plays an important role in marine ecosystems, primarily due to its contribution to nutrient cycling. Whale feces is rich in nutrients such as nitrogen and phosphorus and can stimulate the growth of phytoplankton, which forms the basis of the marine food web.
Bruce Weir is a prominent statistician known for his contributions to statistical genetics, computational statistics, and bioinformatics. His work often focuses on developing statistical methods to analyze genetic data and understand the complexities of biological systems. He has authored numerous publications and is regarded as an influential figure in the field of statistics, particularly in relation to genetics and the application of statistical methods to biological research.
Bet hedging is a biological strategy used by organisms to cope with environmental uncertainty and variability. It involves employing a range of tactics to maximize survival and reproductive success across different conditions, rather than adapting to a single, specific environment. This concept can be understood in the context of evolutionary biology and ecology.
The Institute of Biochemistry and Biophysics (IBB) is a research institute typically associated with scientific studies in the fields of biochemistry and biophysics. While there are several institutes around the world that may use this name or a variation of it, one of the most notable is the Institute of Biochemistry and Biophysics at the University of Warsaw in Poland.
The International Union for Pure and Applied Biophysics (IUPAB) is a global organization that promotes the advancement of biophysics as a scientific discipline. Founded in 1951, IUPAB serves as an international platform for scientists and researchers involved in the study of biological systems through the principles and methods of physics and chemistry. IUPAB's objectives include fostering international collaboration, supporting research and education in biophysics, and promoting the dissemination of knowledge in the field.
The Max Planck Institute for Multidisciplinary Sciences is part of the Max Planck Society, a leading organization in Europe for basic research. This institute focuses on interdisciplinary research that spans various scientific fields, including physics, chemistry, and biology. Located in Göttingen, Germany, it aims to bring together researchers from different disciplines to foster innovation and facilitate collaboration. Researchers at the institute often work on complex problems that require knowledge and techniques from multiple scientific areas.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 2.
    You can publish local OurBigBook lightweight markup files to either https://OurBigBook.com or as a static website
    .
    Figure 3.
    Visual Studio Code extension installation
    .
    Figure 4.
    Visual Studio Code extension tree navigation
    .
    Figure 5.
    Web editor
    . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
    Video 4.
    OurBigBook Visual Studio Code extension editing and navigation demo
    . Source.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact