While this has some of the metrics features that Ciro Santilli wants to implement for OurBigBook.com, it limits the number of articles your readeres can read.
Poor renaming choice.
Or: how to learn X.
That is the wrong question.
Then, once you decide to try one, if that involves programming, only then learn to program to achieve that goal. And don't stop learning what's needed until you either get the thing done, or decide that it is actually not a good idea, or not possible, or that there is something else more important to be done first.
But if doesn't involve programming, then don't learn to program, and learn whatever you actually need to reach that goal instead.
Having that goal is the only way to be motivated to do something.
This is the essence of backward design.
Another very important point to keep in mind is: Section "When in doubt, choose the course that has the most experimental work".
Ciro Santilli wants to rule this with OurBigBook.com.
The only explanation is that the dinosaurs who created the projects are unable to adapt to new superior technologies.
Yes, Ciro is talking to you, big fundamental projects from last century: Linux kernel, GNU Compiler Collection (gcc.gnu.org/lists.html), Binutils (sourceware.org/binutils/), etc.
Some of you are already using Bugzilla for the bugs, so kudos. But if you've seen their benefit, why you still use the mailing list for patches?
Advantages of mailing lists:
- threaded replies, which almost no issue tracker has. GitHub feature request: github.com/isaacs/github/issues/837
Disadvantages: everything else:
- cannot subscribed to a single thread. Which forces you to create an email filter for each one of them you subscribe to.
- no metadata, notably the notion of closing / merging, but also upvotesYou have to read thirty messages before you can know if the bug was solved or not.
- it is insanely hard to reply to messages from before you were subscribed: webapps.stackexchange.com/questions/23197/reply-to-mailman-archived-message/115088#115088
- hard to apply patches locally to test them out: stackoverflow.com/questions/5062389/how-to-use-git-am-to-apply-patches-from-email-messages/49082916#49082916Unless they use Patchwork, which adds one more website on top of the mess.And then Gmail corrupts your patches, and you are forced to use
git send-email, which does not work on some network configurations: stackoverflow.com/questions/28038662/how-to-solve-unable-to-initialize-smtp-properly-when-using-using-git-send-ema or setup ThunderBird. - often have to subscribe to post at all, thus cluttering your inbox further
- you can edit posts to make them clearer.Yes, people could vandalize their answers when they get mad, and threads might stop making sense after edits. But this can be solved with an undeletable post history like Stack Overflow has (but not any other tracker does).Or archive.org :-)In any case, what do you think will happen more often and have greater impact:
- people vandalize their posts
- people fix their silly typos and improve content
- searchable by author, keyword, etc. without Google. Yes, mailing list trackers could have decent implementations to overcome that. But no, GNU Mailman which everyone uses does not have it. Google barely indexes it.
- people have to learn about top posting vs inline posting, and this requires infinite education of new users
- On mailing lists: either put a comment in the middle of a huge patch and let other people find it, or (more likely) copy paste the part of the patch that you are talking about.
- most mail web UIs suck.OK, this is not an unsolvable or intrinsic problem, but still a problem.E.g.:
ezmlmit is not possible to see the entire content in a single page: gcc.gnu.org/ml/gcc/2015-07/threads.html.The alternative: do like LLVM and send attachments. Yes, I we all love opening up attachments on our browsers.The real solution: everyone can create branches and pull requests. Also has the benefit of running CI on the pull requests.
Not sure:
- you can have infinitely many trackers to replicate data in case apocalypse happens in some part of the world.Although I'm not sure this is an advantage, as you don't know anymore which one is the canonical trackers an advantage, as you don't know anymore which one is the canonical tracker.And all web interfaces already have an API to export messages, and someone has already scripted it to import from any web UI to any web UI for you.
As of 2019, the silicon industry is ending, and molecular biology technology is one of the most promising and growing field of engineering.
Ciro Santilli is especially excited about DNA-related technologies, because DNA is the centerpiece of biology, and it is programmable.
First, during the 2000's, the cost of DNA sequencing fell to about 1000 USD per genome in the end of the 2010's: Figure 2. "Cost per genome vs Moore's law from 2000 to 2019", largely due to "Illumina's" technology.
The medical consequences of this revolution are still trickling down towards medical applications of 2019, inevitably, but somewhat slowly due to tight privacy control of medical records.
Ciro Santilli predicts that when the 100 dollar mark is reached, every person of the First world will have their genome sequenced, and then medical applications will be closer at hand than ever.
But even 100 dollars is not enough. Sequencing power is like computing power: humankind can never have enough. Sequencing is not a one per person thing. For example, as of 2019 tumors are already being sequenced to help understand and treat them, and scientists/doctors will sequence as many tumor cells as budget allows.
Then, in the 2010's, CRISPR/Cas9 gene editing started opening up the way to actually modifying the genome that we could now see through sequencing.
What's next?
Ciro believes that the next step in the revolution could be could be: de novo DNA synthesis.
This technology could be the key to the one of the ultimate dream of biologists: cheap programmable biology with push-button organism bootstrap!
Just imagine this: at the comfort of your own garage, you take some model organism of interest, maybe start humble with Escherichia coli. Then you modify its DNA to your liking, and upload it to a 3D printer sized machine on your workbench, which automatically synthesizes the DNA, and injects into a bootstrapped cell.
You then make experiments to check if the modified cell achieves your desired new properties, e.g. production of some protein, and if not reiterate, just like a software engineer.
Of course, even if we were able to do the bootstrap, the debugging process then becomes key, as visibility is the key limitation of biology, maybe we need other cheap technologies to come in at that point.
This a place point we see the beauty of evolution the brightest: evolution does not require observability. But it also implies that if your changes to the organism make it less fit, then your mutation will also likely be lost. This has to be one of the considerations done when designing your organism.
Other cool topic include:
- computational biology: simulations of cell metabolism, protein and small molecule, including computational protein folding and chemical reactions. This is basically the simulation part of omics.If we could only simulate those, we would basically "solve molecular biology". Just imagine, instead of experimenting for a hole year, the 2021 Nobel Prize in Physiology and Medicine could have been won from a few hours on a supercomputer to determine which protein had the desired properties, using just DNA sequencing as a starting point!
- microscopy: crystallography, cryoEM
- analytical chemistry: mass spectroscopy, single cell analysis (Single-cell RNA sequencing)
Ciro is sad that by the time he dies, humanity won't have understood the human brain, maybe not even a measly Escherichia coli... Heck, even key molecular biology events are not yet fully understood, see e.g. transcription regulation.
One of the most exciting aspects of molecular biology technologies is their relatively low entry cost, compared for example to other areas such as fusion energy and quantum computing.
This is the most important technical tutorial project that Ciro Santilli has done in his life so far as of 2019.
The scope is insane and unprecedented, and goes beyond Linux kernel-land alone, which is where it started.
It ended up eating every system programming content Ciro had previously written! Including:
so that that repo would better be called "System Programming Cheat". But "Linux Kernel Module Cheat" sounds more hardcore ;-)
Other major things that could be added there as well in the future are:
- github.com/cirosantilli/algorithm-cheat
- computer architecture tutorials with gem5
Due to this project, some have considered Ciro to be (archive):which made Ciro smile, although "Linux kernel documenter God" would have been more precise.
some kind of Linux kernel god.
[ 1.451857] input: AT Translated Set 2 keyboard as /devices/platform/i8042/s1│loading @0xffffffffc0000000: ../kernel_modules-1.0//timer.ko
[ 1.454310] ledtrig-cpu: registered to indicate activity on CPUs │(gdb) b lkmc_timer_callback
[ 1.455621] usbcore: registered new interface driver usbhid │Breakpoint 1 at 0xffffffffc0000000: file /home/ciro/bak/git/linux-kernel-module
[ 1.455811] usbhid: USB HID core driver │-cheat/out/x86_64/buildroot/build/kernel_modules-1.0/./timer.c, line 28.
[ 1.462044] NET: Registered protocol family 10 │(gdb) c
[ 1.467911] Segment Routing with IPv6 │Continuing.
[ 1.468407] sit: IPv6, IPv4 and MPLS over IPv4 tunneling driver │
[ 1.470859] NET: Registered protocol family 17 │Breakpoint 1, lkmc_timer_callback (data=0xffffffffc0002000 <mytimer>)
[ 1.472017] 9pnet: Installing 9P2000 support │ at /linux-kernel-module-cheat//out/x86_64/buildroot/build/
[ 1.475461] sched_clock: Marking stable (1473574872, 0)->(1554017593, -80442)│kernel_modules-1.0/./timer.c:28
[ 1.479419] ALSA device list: │28 {
[ 1.479567] No soundcards found. │(gdb) c
[ 1.619187] ata2.00: ATAPI: QEMU DVD-ROM, 2.5+, max UDMA/100 │Continuing.
[ 1.622954] ata2.00: configured for MWDMA2 │
[ 1.644048] scsi 1:0:0:0: CD-ROM QEMU QEMU DVD-ROM 2.5+ P5│Breakpoint 1, lkmc_timer_callback (data=0xffffffffc0002000 <mytimer>)
[ 1.741966] tsc: Refined TSC clocksource calibration: 2904.010 MHz │ at /linux-kernel-module-cheat//out/x86_64/buildroot/build/
[ 1.742796] clocksource: tsc: mask: 0xffffffffffffffff max_cycles: 0x29dc0f4s│kernel_modules-1.0/./timer.c:28
[ 1.743648] clocksource: Switched to clocksource tsc │28 {
[ 2.072945] input: ImExPS/2 Generic Explorer Mouse as /devices/platform/i8043│(gdb) bt
[ 2.078641] EXT4-fs (vda): couldn't mount as ext3 due to feature incompatibis│#0 lkmc_timer_callback (data=0xffffffffc0002000 <mytimer>)
[ 2.080350] EXT4-fs (vda): mounting ext2 file system using the ext4 subsystem│ at /linux-kernel-module-cheat//out/x86_64/buildroot/build/
[ 2.088978] EXT4-fs (vda): mounted filesystem without journal. Opts: (null) │kernel_modules-1.0/./timer.c:28
[ 2.089872] VFS: Mounted root (ext2 filesystem) readonly on device 254:0. │#1 0xffffffff810ab494 in call_timer_fn (timer=0xffffffffc0002000 <mytimer>,
[ 2.097168] devtmpfs: mounted │ fn=0xffffffffc0000000 <lkmc_timer_callback>) at kernel/time/timer.c:1326
[ 2.126472] Freeing unused kernel memory: 1264K │#2 0xffffffff810ab71f in expire_timers (head=<optimized out>,
[ 2.126706] Write protecting the kernel read-only data: 16384k │ base=<optimized out>) at kernel/time/timer.c:1363
[ 2.129388] Freeing unused kernel memory: 2024K │#3 __run_timers (base=<optimized out>) at kernel/time/timer.c:1666
[ 2.139370] Freeing unused kernel memory: 1284K │#4 run_timer_softirq (h=<optimized out>) at kernel/time/timer.c:1692
[ 2.246231] EXT4-fs (vda): warning: mounting unchecked fs, running e2fsck isd│#5 0xffffffff81a000cc in __do_softirq () at kernel/softirq.c:285
[ 2.259574] EXT4-fs (vda): re-mounted. Opts: block_validity,barrier,user_xatr│#6 0xffffffff810577cc in invoke_softirq () at kernel/softirq.c:365
hello S98 │#7 irq_exit () at kernel/softirq.c:405
│#8 0xffffffff818021ba in exiting_irq () at ./arch/x86/include/asm/apic.h:541
Apr 15 23:59:23 login[49]: root login on 'console' │#9 smp_apic_timer_interrupt (regs=<optimized out>)
hello /root/.profile │ at arch/x86/kernel/apic/apic.c:1052
# insmod /timer.ko │#10 0xffffffff8180190f in apic_timer_interrupt ()
[ 6.791945] timer: loading out-of-tree module taints kernel. │ at arch/x86/entry/entry_64.S:857
# [ 7.821621] 4294894248 │#11 0xffffffff82003df8 in init_thread_union ()
[ 8.851385] 4294894504 │#12 0x0000000000000000 in ?? ()
│(gdb)Examples:
- classification of finite simple groups
- classification of regular polytopes
- classification of closed surfaces, and more generalized generalized Poincaré conjectures
- classification of associative real division algebras
- classification of finite fields
- classification of simple Lie groups
- classification of the wallpaper groups and the space groups
There are unlisted articles, also show them or only show them.