Archaea are a major evolutionary lineage distinct from bacteria. The cellular comparison here concerns the prokaryotic members of archaea; see two-domain system for broader clade usage. Their biological cells have a nucleoid rather than a membrane-bounded cell nucleus, yet aspects of DNA replication, transcription and biological translation resemble those of eukaryotes. Their characteristic lipids differ chemically from the usual bacterial membrane lipids, and their cell walls, when present, lack peptidoglycan. See OpenStax Biology 2e, 22.2: archaeal distinctions.
Some archaea perform methanogenesis, producing methane as part of their metabolism. Archaea also inhabit ordinary soils and oceans: extreme habitats do not define the lineage. See OpenStax Biology 2e, 22.1: moderate and extreme environments. Woese and Fox's 1977 analysis of ribosomal RNA distinguished the methanogenic group they called archaebacteria from typical bacteria. Their proposed three primary lines of descent were a historical interpretation, rather than the final resolution of deep phylogenetics. See Woese and Fox, 1977: Phylogenetic structure of the prokaryotic domain.

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