Past exam of the mathematics course of the University of Cambridge 2019 iii Paper 207 5 a Solution 2026-10-03
In a proportional hazards model, individual hasThe exponential term is the hazard multiplier relative to the baseline hazard . With unspecified, the Cox partial likelihood multiplies, over event times, the failing subject's multiplier divided by the sum of multipliers in the current risk set. After estimating , the Breslow estimator is
A Stratified Cox model uses a separate baseline hazard for each stratum but a common . Its partial likelihood is the product of within-stratum partial likelihoods, and a separate integrated baseline hazard is estimated in each stratum.
In a matched pair, the only informative comparison occurs while both members remain at risk. If the exposed member fails first, the pair contributes ; if the unexposed member fails first, it contributes . A censoring as the first recorded time gives no informative failure comparison, and any later one-person risk set contributes one. With only two observations per stratum, each stratum supplies almost no information about its arbitrary baseline hazard, so a useful common integrated baseline-hazard estimate is generally unavailable.