Group means are independent random variables with normal distributions
The resulting univariate sampling distributions are
The same variance calculation holds for every , since the difference involves two independent group means. Therefore the standard errors satisfy
Replacing by a common estimated error standard deviation preserves this ratio. Although the individual group means are independent, the contrasts share the baseline mean and have covariance for distinct .
The analysis of variance provides evidence of a chocolate effect both with day included (, p-value ) and with day omitted (, p-value ). Because every chocolate–day cell has the same replication, balanced factorial orthogonality separates the two main effects; the chocolate row is meaningful despite being entered first.
The chocolate-only fitted group means are approximately boards for A, B, C, D respectively. Thus A has the largest fitted lecturing speed and C the smallest. Relative to A, the fitted differences are boards. The printed individual Student t-tests give strong evidence for the A–C contrast (p-value ); B and D versus A have p-values and , respectively. Those latter contrasts are not significant at 5%, and the output does not test all other pairwise comparisons. Simultaneous claims would require accounting for multiple hypothesis testing.
There is little evidence of a day effect after adjusting for chocolate. A chocolate-only normal linear model is therefore a reasonable simpler summary, with residual standard deviation about boards and explained variation . This is an association under the additive statistical model; a causal claim would additionally require an appropriate assignment of chocolate and checks of the regression residuals and possible interaction terms.
For subject and , the random-intercept linear mixed model is
All subject random effects and measurement errors are mutually independent. The fixed effects describe the population mean baseline and weekly gain. Conditional on , a person's observations have independent normal distributions; after integrating out , their covariance is at distinct weeks and their common variance is . Therefore their correlation is .
This Gaussian linear mixed model permits correlated repeated readings while keeping different subjects independent. The fitted standard deviations are kg and kg, giving within-person correlation about . All persons still have the same latent weekly slope in this model.
Allow each subject to have a separate baseline and slope through a correlated random-intercept and random-slope model:
The subject random effects are independent of all measurement errors, and subjects are independent. The within-person covariance between times is , with an additional when the same reading is used twice.
Prefer the model with a random slope. The maximum likelihood estimation refits improve twice the log-likelihood by while adding two covariance statistical parameters. Both the Akaike information criterion ( to ) and Bayesian information criterion ( to ) strongly favour it. The printed nominal likelihood-ratio test is overwhelming. The usual reference chi-squared distribution with two statistical degrees of freedom is not an exact regular calibration, since zero slope variance is a boundary and the intercept–slope correlation is then unidentified; a design-specific parametric bootstrap could calibrate it. This qualification does not undermine the substantial descriptive improvement shown by both information criteria.
The preferred fit estimates population mean baseline strength kg and weekly gain kg/week. The between-person baseline standard deviation is kg, and the between-person slope standard deviation is kg/week. Their estimated correlation is weakly positive, giving random-effect covariance about kg/week; its uncertainty is not supplied. The measurement-error standard deviation is kg. The printed instead describes the correlation between the estimated fixed effects, not between the subject random effects. These statistical parameter estimates come from restricted maximum likelihood; the model comparison uses the separate maximum likelihood estimation fits.
The population mean fitted trajectory is kg. Hence
Using the reported slope standard error, an approximate 95% confidence interval for the population mean gain is kg; a Student t confidence interval with 499 statistical degrees of freedom is almost identical.
Successful individuals can improve far more than the average. Their latent ten-week gains have fitted normal distribution
A clear estimate for an upper-performing group uses a between-person slope quantile: the 95th percentile is kg, and the 97.5th percentile is about kg. The upper 5% of fitted underlying gains begin around 73 kg. These are person-to-person performance quantiles, not confidence intervals for the population mean. Identifying the best observed trainee would require that person's data or fitted subject random effects; the aggregate output cannot identify a literal maximum. If performance means the observed difference of endpoint readings, add the measurement-error variance to the latent gain variance.
At zero a centered normal distribution with standard deviation has density . The two prior standard deviations are and , giving
The wider prior distribution has a lower density at its center.
Under the point hypothesis , the test statistic has a standard normal distribution. The observed statistic is three, giving a two-sided p-value . This is conventionally strong evidence against that point hypothesis. The narrow model is a continuous prior distribution around zero, rather than a point hypothesis.
For and , Normal-normal conjugacy gives
The narrow-model posterior mean is strongly pulled toward zero and its standard deviation is about . The wide-model posterior mean is about , very close to the observation, with standard deviation about . Each model produces a markedly different posterior, so choosing between them requires their predictive evidence.
Use a proper normal distribution prior centered at zero on the log odds ratio. For example,
puts approximately 95 percent of its mass between and , giving odds ratios roughly between and , close to and . Centering at zero treats reciprocal odds ratios symmetrically. If the desired central 95 percent interval is exactly , use standard deviation . A soft prior is appropriate for implausibility, whereas a bounded uniform prior would declare effects outside the limits impossible.
Conditional on , let and independently . The normal distribution with the stated precision parameter can be generated as
Therefore
by the defining normal distribution and chi-squared distribution representation of Student's t-distribution. Its density is
Thus is the location and is the scale, not the standard deviation: . Each study gets its own independent chi-squared draw in this Student t random-effect model.
Fit both the normal and Student t random-effect model with comparable proper prior distributions. Compare priors on the same spread measure: a normal distribution scale is a standard deviation, whereas the standard deviation is .
Use a posterior predictive check: draw study effects and binomial counts from each fitted hierarchy and compare replicated dispersion and extreme study contrasts with the observations. For predicting a new study, generate a new effect from the hierarchy rather than reusing an existing fitted effect. A Leave-one-out cross-validation with entire studies held out can compare integrated predictive probabilities for both arms of each omitted trial, averaging over hyperparameters and its unobserved study effect. Leave-one-study-out influence analysis also reveals whether the difference is driven by a single trial.
Prefer the heavier-tailed hierarchy if it improves the relevant predictive checks and held-out study predictions robustly to reasonable prior choices. The deviance information criterion can supplement the comparison, but its effective parameter count can depend on the latent-variable representation, and six studies give limited information about tail shape. A small numerical criterion difference alone is insufficient evidence.