The Vienna Series in Theoretical Biology is a collection of publications that focus on the integration of theoretical approaches with biological research. The series is primarily associated with the Vienna Institute of Theoretical Biology and aims to explore complex biological systems through mathematical modeling, computational simulations, and other theoretical frameworks. The topics covered in the Vienna Series often include aspects of evolutionary biology, ecological modeling, systems biology, and the dynamics of biological networks.
Vincent Calvez is a mathematician known for his work in the fields of probability theory and mathematical biology. His research often involves stochastic processes and their applications in modeling biological phenomena.
DiProDB is likely a specialized database or repository used for storing and providing access to information related to biomolecular interactions, likely focusing on protein interactions and their associated data. While specific details can vary, databases like DiProDB are used in fields such as bioinformatics, molecular biology, and proteomics to facilitate research by providing curated data on protein-protein interactions, protein-DNA interactions, and other related biological data.
Allen Mouse Brain by Ciro Santilli 40 Updated 2025-07-16
Grouping their mouse brain projcts here.
Video 1.
Tutorial: Allen Developing Mouse Brain by Allen Institute (2014)
Source.
Germline by Ciro Santilli 40 Updated 2025-07-16
It is quite mind blowing when you think about it, that the huge majority of your body's cells is essentially just there to support a tiny ammount of germline, which are the only cells that can actually pass on! It is fun to imagine the cell type tree for this, with a huge branching of somatic cells, and only a few germline going forward.
The Median Voter Theorem (MVT) is a proposition in political science and economics that suggests that in a majority-rule voting system, the preferences of the median voter will ultimately be reflected in the policies adopted by the government. The theorem is based on the assumption that voters have single-peaked preferences, meaning that each voter has a most preferred outcome and their preferences decrease as they move away from that outcome.
The Slutsky equation is an important concept in microeconomics, particularly in the analysis of consumer choice and demand. It helps to decompose the effect of a price change on the quantity demanded of a good into two distinct components: the substitution effect and the income effect.
David E. Shaw is an American entrepreneur, computer scientist, and investor known for his contributions to the field of computational biology and finance. He is the founder of D.E. Shaw Group, a global investment and technology development firm that specializes in quantitative and algorithmic trading. Shaw has a background in computer science, having earned a Ph.D. from Stanford University.
Modified Internal Rate of Return (MIRR) is a financial metric used to evaluate the attractiveness of an investment or project. It improves upon the traditional Internal Rate of Return (IRR) by addressing some of its limitations, particularly the assumptions made regarding reinvestment rates. Here's a breakdown of MIRR: 1. **Definition**: MIRR modifies the IRR by taking into account the cost of capital and the reinvestment rate for cash flows.
The Financial Modelers' Manifesto is a document that outlines best practices and principles for financial modeling, particularly in Excel. It was created by a community of financial modelers who sought to improve the quality and consistency of financial models in practice. The manifesto emphasizes clarity, transparency, and accuracy in financial modeling and aims to guide modelers in creating models that are not only functional but also easy to understand and maintain.
Optimal stopping is a decision-making problem in probability theory and statistics, where one must decide the best time to take a particular action in order to maximize an expected reward or minimize a cost. The key challenge in optimal stopping is that the decision-maker often does not know the future values of the processes involved, making it necessary to make choices based on partial information.
A **self-financing portfolio** is a concept in finance and investment that refers to a portfolio of assets in which any changes in the portfolio's composition are financed entirely through the portfolio's own changes in value, rather than through external cash flows (such as additional investments or withdrawals). In other words, a self-financing portfolio does not require any external funding to maintain or adjust its positions.
Dots and Boxes is a classic pencil-and-paper game typically played by two players. The game involves a grid of dots, where players take turns drawing horizontal or vertical lines between adjacent dots. The objective of the game is to complete as many squares (boxes) as possible. ### Rules: 1. **Setup**: Start with an empty grid of dots. The size of the grid can vary, but a common choice is 4x4 or 5x5 dots.
Fay's trisecant identity is an important result in the theory of elliptic functions and algebraic geometry. It expresses a certain relationship among elliptic functions and their derivatives. In particular, Fay's trisecant identity concerns the trisecant curves associated with an elliptic curve. The identity can be stated in terms of a given elliptic function \( \wp(z) \), which is related to the Weierstrass elliptic functions.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 2.
    You can publish local OurBigBook lightweight markup files to either https://OurBigBook.com or as a static website
    .
    Figure 3.
    Visual Studio Code extension installation
    .
    Figure 4.
    Visual Studio Code extension tree navigation
    .
    Figure 5.
    Web editor
    . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
    Video 4.
    OurBigBook Visual Studio Code extension editing and navigation demo
    . Source.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact