Illumina by Ciro Santilli 40 Updated 2025-07-16
The by far dominating DNA sequencing company of the late 2000's and 2010's due to having the smallest cost per base pair.
Illumina actually bought their 2010's dominating technology from a Cambridge company called Solexa.
To understand how Illumina's technology works basically, watch this video: Video 1. "Illumina Sequencing by Synthesis by Illumina (2016)".
Video 1.
Illumina Sequencing by Synthesis by Illumina (2016)
Source.
The key innovation of this method is the Bridge amplification step, which produces a large amount of identical DNA strands.
Bisulfite sequencing by Ciro Santilli 40 Updated 2025-07-16
The main way to sequence DNA methylation. Converts methylated cytosine to uracil, and then we can sequence those.
Video 1.
Bisulfite Sequencing by Henrik's Lab (2020)
Source. Nothing much new that we don't understand from a single sentence in the animation. But hey, animations!

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