Ciro Santilli @cirosantilli 37

Some of the software-based artificial life simulators can be used as AI training game.

Ciro Santilli just always feels that what can be classified as "artificial life" simulators have too much focus on beating more continuous population mechanics, and lack the discrete elements which he feels could be important to AGI: Section "The missing link between continuous and discrete AI".

There is great interest in this direction of research however quite clearly.

Many/most companies are unable to give any beauty to its employees.

Hiring is simply a process of "let's get this money making project working ASAP", bring people in, without considering Brooks's law.

And then when that happens, companies put people in extremely narrow knowledge areas, making them unable to see or participate in the bigger picture of things, unless they spend 10 years there and reach architect status.

This is perhaps particularly painful for high flying birds like Ciro Santilli.

Companies need a higher top to down force that attempts to actually teach the business and tech to every employee to counter the low level manager get things done now pressure.

Companies that are able to do that, will have many more employees with a sense of purpose, and with the ability to innovate. Those companies will win.

The exact opposite of argument from poor design!

It should be illegal to give someone money to advertise your product.

We should just use tags and upvote-based algorithms.

Advertisement is a form of brainwashing.

TODO find Sergey Brin quote bout advertising being a form of perverting search engine ranking neutrality. In other words, there are neutral metrics to what people find good, like links and upvotes. And then advertising is a way to pervert that to someone's profit.

Sometimes Ciro Santilli thinks advertising should be on-subscription only, but that is too restrictive, e.g. imagine the local business owner who wears a t-shirt of their business.

TODO how to calculate

This is a pre-requisite of Section "Students must have a flexible choice of what to learn".

If the choice of what to learn depend on a years long dependency graph of other obligations, which currently are the increasingly interlinked:you end up without much choice at all.

The lock-in periods must be much more fluid and shorter term than those, otherwise it makes the almost inevitable pivots to success impossible.

This is something that Ciro Santilli has heard from several people at the end of their undergrad/PhD degrees. Some online mentions:

UniProt human: www.uniprot.org/uniprot/Q9BYF1 It is interesting to see in the Mutagenesis how many known mutations can increase or decrease SARS-CoV-2 S protein binding affinity.

Receptor in SARS-CoV-2 cell entry.

This was one of the first notable country-led large scale sequencing efforts of the world.

Sample paper: www.nature.com/articles/ng.3247

The point of these is that they are good for transfection apparently.