NCBI Gene, human gene 7133. Summary and nomenclature give the official symbol TNFRSF1B, its encoded TNF-receptor-family protein, and aliases including TNFR2, CD120b and p75. This is a human entry; species-specific sequence or phenotype claims require their own evidence.

Primary source: www.nature.com/articles/35002131

Verified locator: Nature 403, 339–342, published 20 January 2000, DOI 10.1038/35002131. Primary indexed publisher title/byline: Timothy S. Gardner, Charles R. Cantor and James J. Collins. Abstract verifies synthetic bistability in E. coli and transient chemical or thermal switching.

Additional full-text verification: bioinformatics.cs.vt.edu/~murali/teaching/2003-fall-cs6104/papers/designer/gardner-nature-vol403-genetic-toggle.pdf reproduces the original Nature 403, 339–342 paper. Figure 5 (p. 341) shows individual-cell GFP expression distributions near the switching threshold. Methods, Assay of gene expression (p. 342), identifies the FACSCalibur flow cytometer, 488 nm excitation and 515–545 nm emission filter; Figure 6 distinguishes switching-time observations.

University of Colorado Boulder Parker Research Group primary alumni directory. Grad Students section, Daniela Teixeira entry, records training2001–2005.

September2003 institutional bulletin, PDF page9: laboratory photograph caption identifies Roy Parker in the foreground and colleague Ujwal Sheth. Photograph credit Jeff Topping. The accompanying research account discusses the yeast mRNA-decay investigation. The photograph remains externally hosted.

RNA11,371–382(2005), DOI10.1261/rna.7258505. Primary byline Daniela Teixeira, Ujwal Sheth, Marco A. Valencia-Sanchez, Muriel Brengues and Roy Parker. Abstract: RNA dependence, stress responses and contrasting effects of translation-initiation versus elongation inhibition. Figure6 and associated Results: RNaseA treatment of enriched P-body fractions. Primary archive pmc.ncbi.nlm.nih.gov/articles/PMC1370727/ .

Primary source: mrclmb.ac.uk/news-events/articles/chris-oubridge-1966-2020/

Verified locator: Institutional primary obituary headed Chris Oubridge(1966-2020); opening states death25August2020. Research account identifies U1A/RNA recognition and subsequent spliceosome studies. Named photograph directly linked from the page. Original1994 publisher byline independently verifies Chris Oubridge for DOI10.1038/372432a0.

Official BioFrontiers profile, research on eukaryotic mRNA biogenesis/translation/degradation, affiliations and portrait. Institutional CV experts.colorado.edu/vitas/151440.pdf p.1 confirms 1985 UCSF doctorate; p.3 publication6 identifies the original1987 U2 study. Accessed2026-11-03; original Roy Parker title retained without middle-name expansion.

Science300(5620),805–808(2003), DOI10.1126/science.1082320. Full primary bylines Ujwal Sheth and Roy Parker. Abstract and Figures1–2: functional fluorescent protein fusions localize decay factors; decay-pathway perturbations change foci; decay intermediates localize to these bodies. These observations support localized processing without proving every visible focus is required for all mRNA decay.

Nature372(6505),432–438(1994), DOI10.1038/372432a0. Indexed primary title and byline C.Oubridge, N.Ito, P.R.Evans, C.H.Teo, K.Nagai verify a1.92angstrom RNA-binding-domain/RNA-hairpin crystal structure. Title preserves published A spelling for angstrom. The source heading retains the abbreviated first-author byline. Publisher endpoint www.nature.com/articles/372432a0 was inaccessible; no unverified atom-contact or kinetic constants attributed to it. Existing2009 U1-core paper independently supplies U1A placement at U1 stem-loopII and the distinction between core crystallization and a complete-particle model.

The indexed original publisher record explicitly identifies the first author as Chris Oubridge. Its abstract specifies a21-nucleotide RNA hairpin,ten-nucleotide loop and1.92Å structure,including loop contacts at the protein beta-sheet surface. The primary indexed byline and named MRC obituary now establish the fuller identity; direct publisher open still redirects to an inaccessible identity endpoint. www.nature.com/articles/372432a0

Official Department of Microbiology and Cell Biology profile: Umesh Varshney (IISc Honorary Professor); Research, Protein Synthesis and DNA Repair sections identify research areas and model systems. First faculty image immediately accompanies his profile. Accessed2026-11-03; no inferred birth date, biography dates or awards.

Cell49(2),229–239(1987), DOI10.1016/0092-8674(87)90564-2; PMID3552247. Indexed byline R. Parker, P. G. Siliciano, C. Guthrie. Abstract: two branch-site mutants in an actin-HIS4 fusion, predicted compensating U2 changes and allele-specific biological/biochemical suppression. Full first-author identity verified by Roy Parker’s institutional CV experts.colorado.edu/vitas/151440.pdf , p.1 name and p.3 publication6, also the official laboratory publication list www.colorado.edu/lab/parkergroup/publications (1987). Other indexed initials remain unexpanded.

Journal of Biological Chemistry 266(27), 18018–18024 (1991), DOI 10.1016/S0021-9258(18)55231-5. Indexed byline U. Varshney, C. P. Lee, B. L. Seong, U. L. RajBhandary. Original first-page byline reads Umesh Varshney, Chan Ping Lee, Baik L. Seong and Uttam L. RajBhandary in the indexed original PDF citeseerx.ist.psu.edu/document?doi=c871e93e20447352f0f2e44bfca24f5146d4821a&repid=rep1&type=pdf . Abstract: acceptor-stem and anticodon variants, amber suppression, and one mutant acting at upstream and downstream UAG codons. Full PDF fetch returned cache miss; original indexed first page and primary indexed abstract verified.

Official laboratory biography, “Short biography”: 2007 undergraduate degree, 2013 doctorate on pre-mRNA splicing catalysis, 2014 move to structural postdoctoral work, and 2020 fellowship. Companion departmental profile www.bioch.ox.ac.uk/node/1889921 identifies the same scientist and labels its portrait Sebastian Fica. Checked 2026-11-03; no middle-name expansion or inferred birth date.

Nature458(7237),475–480(2009), DOI10.1038/nature07851; PMID19325628. Primary first-author byline Daniel A.Pomeranz Krummel verified. Abstract, Structure determination and Figures1–4: reconstituted U1 functional core, seven Sm proteins, heavy-atom labeling and 5.5angstrom map. Engineered/truncated particle lacks U1A; Figure5 adds the known U1A–RNA structure to model a complete particle. The crystallographic core must not be described as every component of an intact native U1 particle.

PNAS 84(2), 334–338 (1987), DOI 10.1073/pnas.84.2.334. Primary indexed abstract and initial-only bylines B L Seong and U L RajBhandary verified; no expansion inferred. Anticodon-stem substitutions followed by purification, aminoacylation/formylation, AUG-dependent ribosomal P-site binding, initiation-factor binding and in-vitro protein-synthesis measurements. Full-text repository: pmc.ncbi.nlm.nih.gov/articles/PMC304201/ .

Nature 503, 229–234 (2013), DOI 10.1038/nature12734. Author-hosted original PDF: full first-author byline Sebastian M. Fica, page 229; co-first-author contribution marked. Abstract and Figures 1–3: sulfur substitution/metal rescue in assembled yeast spliceosomes identifies U6 ligands positioning catalytic metals during both splicing reactions. No claim of protein-free splicing by the intact cellular machinery.

Original experimental article, Cell46(6),827–835(1986), DOI10.1016/0092-8674(86)90064-4. Institutional primary abstract: co-transfection of mutant adenovirus E1A and human U1 genes, efficient rescue at donor position+5 but weak rescue at another site position+3; base pairing necessary but insufficient. Published initials retained; no expansion of Weiner identity inferred.

Nature 480, 520–524 (2011), DOI 10.1038/nature10625. Primary byline Nevin D Young verified. Abstract and Figures 1–3: legume model, draft genome assembly, duplicated genomic regions and nodule-enhanced gene comparisons. Full text pmc.ncbi.nlm.nih.gov/articles/PMC3272368/ . No expansion of the middle initial or inferred personal dates.

RNA19(2),141–157(2013), DOI10.1261/rna.035667.112. First-author full byline William R Jeck verified. Abstract and Figures1–4: RNA sequencing with/without RNaseR, enrichment of backsplice junctions and complementary validation. Study-level support for many endogenous circular RNAs, not a universal claim that every resistant transcript is circular or that all circular RNAs are noncoding.

Journal of General Physiology36(1),39–56(1952); DOI10.1085/jgp.36.1.39. Original byline A.D.Hershey and Martha Chase retained. University-hosted original scan www.mun.ca/biology/scarr/Hershey_%26_Chase_1952_J_Gen_Physiol_36%2C39-56.pdf ; primary indexed text pp.50–53, including p.52: Waring-blender stripping, centrifugation of extracellular sulfur label and comparison of transfer to progeny. The scanned PDF opens but text extraction is limited; precise indexed primary passages and original abstract used. No full-name inference from Hershey initials.