KaTeX by Ciro Santilli 40 Updated 2025-07-16
Default mathematics typesetting used in OurBigBook Markup.
Key issues:
Ciro Santilli once visited the chemistry department of a world leading university, and the chemists there were obsessed with NMR. They had small benchtop NMR machines. They had larger machines. They had a room full of huge machines. They had them in corridors and on desk tops. Chemists really love that stuff. More precisely, these are used for NMR spectroscopy, which helps identify what a sample is made of.
Basically measures the concentration of certain isotopes in a region of space.
Video 1.
Introduction to NMR by Allery Chemistry
. Source.
Video 2.
How to Prepare and Run a NMR Sample by University of Bath (2017)
Source. This is a more direct howto, cool to see. Uses a Bruker Corporation 300. They have a robotic arm add-on. Shows spectrum on computer screen at the end. Shame no molecule identification after that!
Video 3. Source.
This video has the merit of showing real equipment usage, including sample preparation.
Says clearly that NMR is the most important way to identify organic compounds.
Video 4.
Introductory NMR & MRI: Video 01 by Magritek (2009)
Source. Precession and Resonance. Precession has a natural frequency for any angle of the wheel.
Video 5.
Introductory NMR & MRI: Video 02 by Magritek (2009)
Source. The influence of temperature on spin statistics. At 300K, the number of up and down spins are very similar. As you reduce temperature, we get more and more on lower energy state.
Video 6.
Introductory NMR & MRI: Video 03 by Magritek (2009)
Source. The influence of temperature on spin statistics. At 300K, the number of up and down spins are very similar. As you reduce temperature, we get more and more on lower energy state.
Video 7.
NMR spectroscopy visualized by ScienceSketch
. Source. 2020. Decent explanation with animation. Could go into a bit more numbers, but OK.
smashkarts.io by Ciro Santilli 40 Updated 2025-07-16
Quite good, Ciro Santilli played this a lot in 2021/2022, his user ID: ofo5fNy7wRNC1Cw94YVB4KMOW5f2.
The physics not as good as the original Mario Kart 64, and it is notably missing jump gliding, and generally not as sharp! But it is really not bad.
Some of the weapons were too useless that you are just better firing them straight away at wall immediately to get something better, they could have a little better balancing there. I'm talking about you gatling that takes 10 seconds to finish firing, and does not kill enemies immediately. You are better off just firing that gun immediately when you get it to be able to get another gun ASAP. They seem to have done some balancing there however.
It had no chat option, but in a way it was cool to be forced to communicate non-verbally with people whose usernames you got familiar with. Funny you can love people like that, without ever talking to them. The best way of doing so being tea-bagging by going back and forth on a player after winning.
Performance was sometimes a problem. When Ciro tried it again on December 2022, it was unplayable due to the impossibly large lag. Things were much better again in 2023 however it seems.
If you live in the relatively food abundant environment of another cell, then you don't have to be able to digest every single food source in existence, of defend against a wide range of predators.
And likely you also want to be as small as possible to evade the host's immune system.
Power, Sex, Suicide by Nick Lane (2006) section "Gene loss as an evolutionary trajectory" puts it well:
One of the most extreme examples of gene loss is Rickettsia prowazekii, the cause of typhus. [...] Over evolutionary time Rickettsia has lost most of its genes, and now has a mere  protein-coding genes left. [...] Rickettsia is a tiny bacterium, almost as small as a virus, which lives as a parasite inside other cells. It is so well adapted to this lifestyle that it can no longer survive outside its host cells. [...] It was able to lose most of its genes in this way simply because they were not needed: life inside other cells, if you can survive there at all, is a spoonfed existence.
and also section "How to lose the cell wall without dying" page 184 has some related mentions:
While many types of bacteria do lose their cell wall during parts of their life cycle only two groups of prokaryotes have succeeded in losing their cell walls permanently, yet lived to tell the tale. It's interesting to consider the extenuating circumstances that permitted them to do so.
[...]
One group, the Mycoplasma, comprises mostly parasites, many of which live inside other cells. Mycoplasma cells are tiny, with very small genomes. M. genitalium, discovered in 1981, has the smallest known genome of any bacterial cell, encoding fewer than 500 genes. M. genitalium, discovered in 1981, has the smallest known genome of any bacterial cell, encoding fewer than 500 genes. [...] Like Rickettsia, Mycoplasma have lost virtually all the genes required for making nucleotides, amino acids, and so forth.
Makes RNA from RNA.
Used in Positive-strand RNA virus to replicate.
I don't think it's present outside viruses. Well regulated organisms just transcribe more DNA instead.
SsethTzeentach by Ciro Santilli 40 Updated 2025-07-16
Reviews mostly old RPG and strategy games. And hentai games when it is possible to hide the porn from YouTube. He also sponsors Hentai and uploads it on his website: www.ssethtzeentach.com/nsfw
Ciro Santilli really likes his sense of humor, always going into "politically incorrect" areas, and often making fun of both dictatorships and the USA. He actually knows a bit about politics. Due to the nature of his humour, many of his earlier videos have been taken down from YouTube apparently, www.ssethtzeentach.com/videos mentions:
Ever since going full time, I'm usually very clean and stay out of trouble, but in the past a fair number of my videos were taken down.
The videos are also incredibly packed full of well selected edited-in "memes jokes". He particularly likes very short snippets of gay porn which cannot actually be taken down as porn, even though the obviously are porn excerpts, like the buffed dude blowing a kiss to his tit.
www.youtube.com/watch?v=sw8v5__Ytf4 Heroes of Might and Magic III (2018) is one of the best reviews. Sseth likes to find and make fun of game breaking imbalances, something that Ciro likes due to his Ciro Santilli's self perceived creative personality.
www.youtube.com/watch?v=rOJdDvf-tUs The Sseth Streaming Experience (2019), being a live stream, likely shows more realistically how Seth actually talks in real life.
www.youtube.com/watch?v=yG9g2byXR2c Might and Magic VI (Re)Review is another good video (2021)
Sseth has a certain vaporwave aesthetic, which Ciro also enjoys.
youtu.be/se6Y2o3OqJQ?t=2 shows what could actually be outside of his real window.
Gospel of Matthew 7:13:
Enter through the narrow gate. For wide is the gate and broad is the road that leads to destruction, and many enter through it.
Ciro Santilli really likes this one, because he feels that where many people go, it is useless to go again. It is much better to explore that which few can do, but which many will need.
Also known as being hipster.
Reverse transcriptase by Ciro Santilli 40 Updated 2025-07-16
Converts RNA to DNA, i.e. the inverse of transcription. Found in viruses such as Retrovirus, which includes e.g. HIV.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 2.
    You can publish local OurBigBook lightweight markup files to either https://OurBigBook.com or as a static website
    .
    Figure 3.
    Visual Studio Code extension installation
    .
    Figure 4.
    Visual Studio Code extension tree navigation
    .
    Figure 5.
    Web editor
    . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
    Video 4.
    OurBigBook Visual Studio Code extension editing and navigation demo
    . Source.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact