Ciro Santilli @cirosantilli  40

MacKenzie Bezos's charity instrument.

www.irishtimes.com/life-and-style/people/mackenzie-scott-how-the-former-mrs-bezos-became-a-philanthropist-like-no-other-1.4850049 MacKenzie Scott: How the former Mrs Bezos became a philanthropist like no other (2020) has some good mentions:

The name of the organization is a reference to the old man lost his horse.

www.newyorker.com/magazine/2022/03/07/a-journey-to-the-center-of-our-cells A Journey to the Center of Our Cells (2022) by James Somers comments on M. genitalium in general, and in particular on the JCVI strains.

GPU accelerated, simulates the Craig's minimized M. genitalium, JCVI-syn3A at a particle basis of some kind.

Lab head is the cutest-looking lady ever: chemistry.illinois.edu/zan, Zaida (Zan) Luthey-Schulten.

github.com/CovertLab/WholeCell Arghh, MATLAB. github.com/CovertLab/WholeCellSimDB

www.wholecellviz.org/viz.php awesome visualization of simtk, paper: www.ncbi.nlm.nih.gov/pmc/articles/PMC3413483/ A Whole-Cell Computational Model Predicts Phenotype from Genotype - 2013 - Jonathan R. Karr.

Followed up by the E. Coli Whole Cell Model by Covert Lab.

Each side is a sphere section. They don't have to have the same radius, they are still simple to understand with different radiuses.

The two things you have to have in mind that this does are:

Published as "Fine Structure of the Hydrogen Atom by a Microwave Method" by Willis Lamb and Robert Retherford (1947) on Physical Review. This one actually has open accesses as of 2021, miracle! journals.aps.org/pr/pdf/10.1103/PhysRev.72.241

Microwave technology was developed in World War II for radar, notably at the MIT Radiation Laboratory. Before that, people were using much higher frequencies such as the visible spectrum. But to detect small energy differences, you need to look into longer wavelengths.

This experiment was fundamental to the development of quantum electrodynamics. As mentioned at Genius: Richard Feynman and Modern Physics by James Gleick (1994) chapter "Shrinking the infinities", before the experiment, people already knew that trying to add electromagnetism to the Dirac equation led to infinities using previous methods, and something needed to change urgently. However for the first time now the theorists had one precise number to try and hack their formulas to reach, not just a philosophical debate about infinities, and this led to major breakthroughs. The same book also describes the experiment briefly as:

It is two pages and a half long.

They were at Columbia University in the Columbia Radiation Laboratory. Robert was Willis' graduate student.

Previous less experiments had already hinted at this effect, but they were too imprecise to be sure.

The process that imports proteins encoded in the nuclear DNA and made in the cytosol into the mitochondria.

The term is mentioned e.g. in this article: www.nature.com/articles/nrm2959.

Power, Sex, Suicide by Nick Lane (2006) suggests that proteins are somehow tagged with extra amino acids for this.

Argued at Power, Sex, Suicide by Nick Lane (2006) page 212.

Basically, energy supply has to be modulated rather quickly, because we spend a lot sometimes, and very little other times.

Even not turning it off quickly enough is a problem, as it starts to generate free radicals which fuck you up.

If control came from the nucleus, it has no way to address different mitochondria. But it might be that only one of the mitochondria needs the change. If the nucleus tells all mitochondria to stop producing when only one is full, the others are going to say: "nope, I'm not full, continue producing!" and the one that need to stop will have its signal overridden by the others.

Wikipedia mentions "Since animal mtDNA evolves faster than nuclear genetic markers" with a few sources.

Some sources:

DNA stuff at: human mtDNA.

Big companies like Google are able to publish white papers as peer reviewed papers just due to their reputation, e.g. without giving any source code that is central for the article.

It is insane.

E.g.: AlphaGo is closed source but published as www.nature.com/articles/natnure16961 in 2016 on Nature.