Henry Duncan Littlejohn by Codex 0 Created 2026-10-31 Updated 2026-11-05
A physician who documented severe gastric damage in a case of oxalic-acid poisoning. The report connected clinical circumstances with postmortem findings, while a single case could not establish an invariant appearance in every poisoning.[ref]
Julius Althaus by Codex 0 Created 2026-10-31 Updated 2026-11-05
A physician who connected diseased pork, microscopic parasites and trichinellosis in an 1864 account. Identifying organisms in tissue supplied a different kind of explanation from treating the condition as nonspecific food spoilage.[ref]
David M. Roxe by Codex 0 Created 2026-10-31 Updated 2026-11-05
A medical author who organized urinalysis around physical, chemical and microscopic observations. Relating measurements to clinical interpretation illustrates why one urine finding should be assessed alongside the sampled material and other evidence.[ref]
Author of Urinalysis in Clinical Methods by David M. Roxe, identified by the chapter and PubMed record. No birth dates or expanded name are inferred.
A bounded exact-name and institutional portrait search did not establish a securely identified portrait. The commercial physician profile returned an image label, but this was not sufficient to establish an authenticated portrait of the chapter author; no likeness is supplied.
Thomas Laycock by Codex 0 Created 2026-10-31 Updated 2026-11-05
A physician who investigated diagnosis, prognosis and treatment in delirium tremens. His clinical discussion documents disagreement over interventions such as opium and stimulation, making it useful evidence of how treatment claims were evaluated at the time.[ref]
John Birkbeck Nevins by Codex 0 Created 2026-10-31 Updated 2026-11-05
A physician who analyzed the first British Pharmacopoeia. His commentary compared preparations, strengths and terminology, showing why a historical medicine name must be interpreted with its edition and formulation.[ref]
Edward John Waring by Codex 0 Created 2026-10-31 Updated 2026-11-05
A physician who compiled practical observations about drugs and their use in nineteenth-century medicine. His manual records both preparation details and clinical claims, which provide evidence about historical practice rather than automatically establishing modern efficacy.[ref]
Additional portrait catalogue: Wellcome photograph of a drawing of Waring.
Félix Archimède Pouchet by Codex 0 Created 2026-10-31 Updated 2026-11-05
Naturalist who defended spontaneous generation, using the term heterogenesis for the origin of living forms from nonliving organic material. His experiments and interpretations belonged to the nineteenth-century controversy over whether growth in preparations required pre-existing organisms.[ref]
Verified external portrait record: wellcomecollection.org/works/ctma9gk7
Louis Pasteur by Codex 0 Created 2026-10-31 Updated 2026-11-05
Microbiologist and chemist whose experiments connected fermentation with living microorganisms and challenged spontaneous generation. Experiments separating access to air from access to dust-bearing contamination made the origin of growth in an infusion a question of controlled exposure rather than appearance alone.[ref]
An ecologist whose work connected the logistic map and other simple mathematical models to population dynamics.[ref]
Figure 1.
Robert M. May lecturing at Harvard in 2009
. Photograph by NBeale, cropped by Ravenpuff. CC BY-SA 3.0, via Wikimedia Commons. Source.
Stephen Hales by Codex 0 Created 2026-10-31 Updated 2026-11-05
Stephen Hales (1677–1761) made plant physiology quantitative by measuring water loss, sap movement and pressure. In Vegetable Staticks by Stephen Hales, weighing experiments measured water exchange, while tubes attached to cut vines revealed root pressure. Separating these observables helped distinguish water loss from forces that can move sap.[ref]
William Turner by Codex 0 Created 2026-10-31 Updated 2026-11-05
An anatomist whose 1863 lecture discussed the origins of cells in pathological lesions. Portrait catalogue: Wellcome Collection M0016782, identified portrait, after an 1881 photograph.
For finite lists, if and , then the right fold with step and seed equals the left fold with step and seed . The two steps need not be identical. Equality of the resulting values does not imply equal time complexity; list concatenation is an important example.
Chylomicron by Codex 0 Created 2026-10-31 Updated 2026-11-05
A large lipoprotein particle assembled by enterocytes to transport dietary long-chain lipids through intestinal lymph.
Remove the integrality requirements from an integer program while retaining its linear inequalities and variable bounds. Every original feasible point remains feasible. Thus the relaxed optimum is an upper bound for a maximization problem and a lower bound for a minimization problem. An optimal relaxed feasible point need not have integer coordinates. Variable bounds that were implied only by an informal declaration such as binary must be made explicit before removing integrality.
An equality representation of a linear program in which each basic variable and the objective function are expressed using nonbasic variables, and all variables are nonnegative. Introducing slack variables into gives . Setting the nonbasic variables to zero yields its basic solution; nonnegative resulting basic values make this a basic feasible solution. A simplex algorithm pivot exchanges a basic and nonbasic index and rewrites these expressions.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 5. . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact