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Half-Yearly Report on Pathology and Principles and Practice of Medicine (1865) by
Codex 0 2026-10-31
A pericyte is a vessel-associated biological cell located along the outside of small blood vessels, closely associated with endothelial cells. Pericytes help regulate vessel maturation and barrier properties. In mice with reduced pericyte coverage, vascular permeability and transport across the blood-brain barrier change; this connects a surrounding support cell to the function of the endothelial cell barrier. Coverage, anatomical location and functional evidence should be considered together when identifying pericytes. [ref]
Pericytes regulate the blood–brain barrier by A. Armulik and others. Armulik and others, 2010, abstract and barrier-permeability experiments
A melanocyte is a pigment-producing biological cell that synthesizes melanin in specialized compartments called melanosomes. In skin, melanosomes are transferred to neighbouring keratinocytes, so the site of pigment production differs from much of its final distribution. Melanin helps attenuate ultraviolet radiation; differences in pigmentation depend on pigment production and handling, rather than simply the number of melanocytes. [ref]
A specialized contact connecting neighbouring biological cells or connecting a cell to its surroundings.
Different junctions perform different tasks: an adherens junction mechanically couples cells, a tight junction regulates passage between them, and a gap junction permits selected intercellular exchange. The shared category therefore specifies an organized contact rather than one universal permeability or mechanical function. [ref]
A giant cell is a conspicuously large biological cell, often containing several cell nuclei. It can arise by fusion of separate biological cells or by repeated nuclear division without completed cytokinesis. These routes differ experimentally: more DNA or more nuclei does not establish that cell fusion occurred. Macrophage fusion produces some inflammatory giant cells, whereas normal specialized large cells also occur. The term describes morphology rather than one developmental lineage. [ref]
Molecular Biology of the Cell, 4th edition by Bruce Alberts and others. Chapter 18, Cytokinesis: nuclear division and cytoplasmic separation
Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
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Intro to OurBigBook
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