Cult leader Updated +Created
Cultured meat Updated +Created
This is something worth investigating!
Video 1.
Inside the Quest to Make Lab Grown Meat by WIRED (2018)
Source.
Interviews with a few startups in the area, most of the time with Eat Just.
youtu.be/QO9SS1NS6MM?t=217 taught Ciro Santilli something he really appreciated: uncanny valley.
Cycling Updated +Created
Ciro Santilli's sport of choice circa 2020, see also: Ciro Santilli's cycling.
Daisy chain Bitcoin inscription Updated +Created
This is a term invented by Ciro Santilli, and refers to a loose set of uncommon Bitcoin inscription methods that involve inscribing one or a small number of payloads per Bitcoin transaction.
These methods are both inefficient and hard to detect and decode, partly because Bitcoin Core does not index spending transactions: bitcoin.stackexchange.com/questions/61794/bitcoin-rpc-how-to-find-the-transaction-that-spends-a-txo. This makes finding them all that more rewarding however.
On the other hand, they do have the advantage of not depending on any block size limits, as their individual transactions are very small.
Inscribing anything large would however take a very long time, as you'd have to wait until the previous payload chunk is confirmed before going to the next one. This alone makes the format impractical perhaps.
Dan Abramson Updated +Created
Dan, if you ever Google yourself here, please contact Ciro Santilli: Section "How to contact Ciro Santilli" to do something with OurBigBook.com. Cheers.
Dan Dascalescu Updated +Created
David Tong Updated +Created
A charismatic, perfect-English-accent (Received Pronunciation) physicist from University of Cambridge, specializing in quantum field theory.
He has done several "vulgarization" lectures, some of which could be better called undergrad appetizers rather, a notable example being Video "Quantum Fields: The Real Building Blocks of the Universe by David Tong (2017)" for the prestigious Royal Institution, but remains a hardcore researcher: scholar.google.com/citations?hl=en&user=felFiY4AAAAJ&view_op=list_works&sortby=pubdate. Lots of open access publications BTW, so kudos.
The amount of lecture notes on his website looks really impressive: www.damtp.cam.ac.uk/user/tong/teaching.html, he looks like a good educator.
David has also shown some interest in applications of high energy mathematical ideas to condensed matter, e.g. links between the renormalization group and phase transition phenomena. TODO there was a YouTube video about that, find it and link here.
Ciro Santilli wonders if his family is of East Asian, origin and if he can still speak any east asian languages. "Tong" is of course a transcription of several major Chinese surnames and from looks he could be mixed blood, but as mentioned at www.ancestry.co.uk/name-origin?surname=tong it can also be an English "metonymic occupational name for a maker or user of tongs". After staring at his picture for a while Ciro is going with the maker of tongs theory initially.
De-banking should be illegal Updated +Created
Courts of law should decide if your money is legal or not. Not private entities such as banks. This is actually a case for cryptocurrencies and central bank digital currencies.
Ciro Santilli had a fun mini-case of this with his Barclays account frozen for a few days in 2024 in the UK after receiving a large anonymous cryptocurrency donatio: Barclays regulation.
DeepMind Updated +Created
They seem to do some cool stuff.
They have also declined every one of Ciro Santilli's applications for software engineer jobs before any interview. Ciro always wondered what does it take to get an interview with them. Lilely a PhD? Oh well.
In the early days at least lots of gamedev experience was enough though: www.linkedin.com/in/charles-beattie-0695373/.
Deep tech Updated +Created
Ciro Santilli is a fan of this late 2010's buzzword.
It basically came about because of the endless stream of useless software startups made since the 2000's by one or two people with no investments with the continued increase in computers and Internet speeds until the great wall was reached.
Deep tech means not one of those. More specifically, it means technologies that require significant investment in expensive materials and laboratory equipment to progress, such as molecular biology technologies and quantum computing.
And it basically comes down to technologies that wrestle with the fundamental laws of physics rather than software data wrangling.
Computers are of course limited by the laws of physics, but those are much hidden by several layers of indirection.
Full visibility, and full control, make computer tasks be tasks that eventually always work out more or less as expected.
The same does not hold true when real Physics is involved.
Physics is brutal.
To start with, you can't even see your system very clearly, and often doing so requires altering its behaviour.
For example, in molecular biology, most great discoveries are made after some new technique is made to be able to observe smaller things.
But you often have to kill your cells to make those observations, which makes it very hard to understand how they work dynamically.
What we would really want would be to track every single protein as it goes about inside the cell. But that is likely an impossible dream.
The same for the brain. If we had observations of every neuron, how long would it take to understand it? Not long, people are really good at reverse engineering things when there is enough information available to do so, see also science is the reverse engineering of nature.
Then, even when you start to see the system, you might have a very hard time controlling it, because it is so fragile. This is basically the case of quantum computing in 2020.
It is for those reasons that deep tech is so exciting.
The next big things will come from deep tech. Failure is always a possibility, and you can't know before you try.
But that's also why its so fun to dare.
Stuff that Ciro Santilli considers "deep tech" as of 2020:
Deletionism on Wikipedia Updated +Created
Some examples by Ciro Santilli follow.
Of the tutorial-subjectivity type:
Notability constraints, which are are way too strict:
  • even information about important companies can be disputed. E.g. once Ciro Santilli tried to create a page for PsiQuantum, a startup with $650m in funding, and there was a deletion proposal because it did not contain verifiable sources not linked directly to information provided by the company itself: en.wikipedia.org/wiki/Wikipedia:Articles_for_deletion/PsiQuantum Although this argument is correct, it is also true about 90% of everything that is on Wikipedia about any company. Where else can you get any information about a B2B company? Their clients are not going to say anything. Lawsuits and scandals are kind of the only possible source... In that case, the page was deleted with 2 votes against vs 3 votes for deletion.
    should we delete this extremely likely useful/correct content or not according to this extremely complex system of guidelines"
    is very similar to Stack Exchange's own Stack Overflow content deletion issues. Ain't Nobody Got Time For That. "Ain't Nobody Got Time for That" actually has a Wiki page: en.wikipedia.org/wiki/Ain%27t_Nobody_Got_Time_for_That. That's notable. Unlike a $600M+ company of course.
    In December 2023 the page was re-created, and seemed to stick: en.wikipedia.org/wiki/Talk:PsiQuantum#Secondary_sources It's just a random going back and forth. Author Ctjk has an interesting background:
    I am a legal official at a major government antitrust agency. The only plausible connection is we regulate tech firms
There are even a Wikis that were created to remove notability constraints: Wiki without notability requirements.
For these reasons reason why Ciro basically only contributes images to Wikipedia: because they are either all in or all out, and you can determine which one of them it is. And this allows images to be more attributable, so people can actually see that it was Ciro that created a given amazing image, thus overcoming Wikipedia's lack of reputation system a little bit as well.
Wikipedia is perfect for things like biographies, geography, or history, which have a much more defined and subjective expository order. But when it comes to "tutorials of how to actually do stuff", which is what mathematics and physics are basically about, Wikipedia has a very hard time to go beyond dry definitions which are only useful for people who already half know the stuff. But to learn from zero, newbies need tutorials with intuition and examples.
Bibliography:
De novo DNA synthesis Updated +Created
As of 2018, Ciro Santilli believes that this could be the next big thing in biology technology.
"De novo" means "starting from scratch", that is: you type the desired sequence into a computer, and the synthesize it.
The "de novo" part is important, because it distinguishes this from the already well solved problem of duplicating DNA from an existing DNA template, which is what all our cells do daily, and which can already be done very efficiently in vitro with polymerase chain reaction.
Many startup companies are attempting to create more efficient de novo synthesis methods:
Notably, the dream of most of those companies is to have a machine that sits on a lab bench, which synthesises whatever you want.
TODO current de novo synthesis costs/time to delivery after ordering a custom sequence.
The initial main applications are likely going to be:
but the real pipe dream is building and bootstraping entire artificial chromosomes
News coverage:
Video 1.
Nuclera eDNA enzymatic de novo DNA synthesis explanatory animation (2021)
Source. The video shows nicely how Nuclera's enzymatic DNA synthesis works:
Dialog between Fisherman and Woodcutter Updated +Created
Lit: fish timber question answer.
The dialog is also known as allegory for an incredibly deep philosophical discussion between an idealized wise woodcutter and a fisherman, e.g. mentioned at: www2.kenyon.edu/Depts/Religion/Fac/Adler/Writings/Fisherman%20and%20Woodcutter.pdf
This song is just too slow for Ciro Santilli to make much out of it.
Figure 1.
Dialog between Fisherman and Woodcutter Chinese traditional painting by Xie Shichen
.
Video 2.
Dialog between Fisherman and Woodcutter performed by Wu Jinglüe
. Source. Accompagnied by di flute to reinforce the idea of two voices. This one has TODO year.