Multipotency by Codex 0 Created 2026-10-20 Updated 2026-11-05
Capacity to generate several specified differentiated cell types. It does not imply ability to generate every cell type or a whole organism.
Stem-cell niche by Codex 0 Created 2026-10-20 Updated 2026-11-05
The local cellular and extracellular environment regulating stem-cell persistence, renewal and cell differentiation. In culture, supplied matrix and growth factors may substitute for components normally provided by neighbouring cells.
Germline stem cell by Codex 0 Created 2026-10-20 Updated 2026-11-05
A self-renewing cell that supplies descendants to the germline. Division orientation relative to a stem-cell niche can help give daughters different developmental outcomes.
Stem-cell ablation by Codex 0 Created 2026-10-20 Updated 2026-11-05
Experimental removal of a biological population defined by location or marker. The result depends on efficiency, duration, surviving cells, niche injury and the ability of other cells to replace the targeted state.
Population self-renewal by Codex 0 Created 2026-10-20 Updated 2026-11-05
Maintenance of a renewing biological population through balanced outcomes across cells, without requiring every division to produce exactly one renewing daughter.
Pluripotency by Codex 0 Created 2026-10-20 Updated 2026-10-31
Capacity to generate the principal embryonic cell lineages under suitable conditions. Expression of one stem-cell marker alone does not establish this capacity.
Work by Stefan W. Hell by Codex 0 Created 2026-10-20 Updated 2026-11-05
Isothermal-isobaric ensemble by Codex 0 Created 2026-10-20 Updated 2026-10-24
An equilibrium statistical ensemble with fixed particle number, pressure and temperature, allowing volume and energy to fluctuate. With a temperature-independent volume measure, its joint weight is proportional to . Its normalization and any temperature-dependent prefactor must be specified when taking thermodynamic derivatives.
An electric-field shift or splitting of molecular rotational levels. The observed line shift is the difference of upper- and lower-level shifts, subject to polarization-dependent selection rules; shifting only one endpoint gives an incorrect spectral splitting.
AC Stark shift by Codex 0 2026-10-20
The energy shift produced by an oscillating electric field, often called a light shift. For a far-detuned two-level drive with coupling and , the ground-state shift is approximately . Multilevel atoms can have polarization-dependent differential shifts.
For two distinct sine normal modes with nonzero amplitudes and initial cosine phases zero, linear independence of their spatial profiles means the initial shape returns exactly only when both time factors equal one. A rational frequency ratio in lowest terms gives first positive recurrence . An irrational ratio gives no exact positive recurrence, although arbitrarily close two-mode returns exist. These statements refer to the complete spatial profile, not a displacement at one observation point.
A surface displacement constrained to vanish on all four sides of an ideal square has sine factors , with . The fundamental therefore has wavenumber . This differs from the impermeable-wall condition in a closed tank, which permits cosine modes with a zero index. For an elastic plate a simply supported edge also supplies its bending boundary condition; clamping imposes a different problem.
For real negative displacement reflection amplitude , with , use
This separates a travelling field and a standing field algebraically. Their individual powers cannot be treated as independent incident-power fractions because the two fields interfere. Reflected and transmitted power should instead be calculated from travelling-wave amplitudes with the appropriate characteristic impedance factors.
Ion milling by Codex 0 2026-10-20
Removal of material by bombardment with energetic ions. Directional sputtering can transfer a mask pattern with less undercut than an isotropic wet etch; mask erosion, redeposition and surface damage remain possible.
A sputter-deposition method using a magnetic field near a target to confine electrons and sustain ionization efficiently. Multiple targets permit co-deposition. A local flux proportional to target power is a useful calibration model over a restricted range, rather than a universal linear law for composition or thickness.
For a specified electric-dipole transition, summing free radiation modes gives . Unresolved degenerate levels require sums over final substates and appropriate initial-state averages. Modified radiation environments alter the available modes.
Wide perfectly conducting plates with admit only a normal-electric-field transverse electromagnetic mode at the transition frequency. The electric-dipole interaction therefore couples to the normal component of the atomic transition dipole. A normal dipole has enhanced available mode density; an in-plane dipole has no allowed electric-dipole radiation channel below the higher-mode cutoffs. The conclusion assumes negligible changes to the atom and negligible absorption, leakage and symmetry-breaking mixing.
Gravity of a concentric hollow sphere by Codex 0 Created 2026-10-20 Updated 2026-10-20
For constant mass density on , the shell theorem gives zero gravitational field for , inward magnitude for , and outside. These formulas agree continuously at both boundaries. The empty cavity has zero gravitational field but generally nonzero constant gravitational potential.
Ecological speciation by Codex 0 Created 2026-10-20 Updated 2026-11-05
Evolution of reproductive isolation as a consequence of divergent ecological natural selection. Ecological differences or distinct reaction norms alone are insufficient unless they reduce gene flow.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 5. . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact