Past exam of the mathematics course of the University of Cambridge 2024 iii Paper 207 4 a iii Solution Created 2026-09-24 Updated 2026-09-25
Past exam of the mathematics course of the University of Cambridge 2024 iii Paper 207 4 b Solution Created 2026-09-24 Updated 2026-09-25
Let be the at-risk process and the counting process for observed events. Over a short interval, the multiplicative-intensity model giveswhere is the hazard function and the cumulative hazard function. Solving this relation for the infinitesimal hazard increment suggests . Summing over distinct event times gives the Nelson–Aalen estimatorwhere events occur among individuals at risk. Here there are no ties, so .
Past exam of the mathematics course of the University of Cambridge 2024 iii Paper 207 5 a i Solution Created 2026-09-24 Updated 2026-09-25
Writing the two functions in the question as survivor functions, . Since ,Differentiating at times where the hazard functions exist gives . Their hazard ratio is therefore the constant , so they form a proportional hazards family.
Past exam of the mathematics course of the University of Cambridge 2024 iii Paper 207 5 a Solution Created 2026-09-24 Updated 2026-09-25
A proportional hazards family has hazard functions related bywhere the hazard ratio is positive and independent of time. Equivalently, its cumulative hazard functions satisfy and its survivor functions satisfy .
Past exam of the mathematics course of the University of Cambridge 2024 iii Paper 207 6 b i Solution Created 2026-09-24 Updated 2026-09-25
Construct the two countries' period-specific risk sets with the same left truncation and right censoring rules, then compare their event counts by a Log-rank test. This is a nonparametric comparison because it does not specify the shape of either country's hazard function.