Neil Fernandez by Ciro Santilli 37 Updated 2025-07-16
“Especially my father. He was doing most of it and he is a savoury, strong character. He has strong beliefs about the world and in himself, and he was helping me a lot, even when I was at university as an undergraduate.”
An only child, Arran was born in 1995 in Glasgow, where his parents were studying at the time. His father has Spanish lineage, having a great grandfather who was a sailor who moved from Spain to St Vincent in the Carribean. A son later left the islands for the UK where he married an English woman. Arran’s mother is Norwegian.
“My father was writing and my mother is an economist. They both worked from home which also made things easier,” Arran says.
A bit like what Ciro Santilli feels about himself!
One of the articles says his father has a PhD. TODO where did he work? What's his PhD on? Photo: www.topfoto.co.uk/asset/1357880/
www.thetimes.co.uk/article/the-everyday-genius-pxsq5c50kt9:
Neil, a political economist, attended state and private schools in Hampshire but was also taught for a period at home by his mother.
It’s strange because for most people maths is a real turn-off, yet maths is all about patterns and children of two or three love patterns. It just shows that schools are doing something seriously wrong.”
Peptidoglycan by Ciro Santilli 37 Updated 2025-07-16
From the Wikipedia image we can see clearly the polymer structure formed: it is a mesh with:
Figure 1.
Peptidoglycan polymer structure
. Source.
Binds an amino acid to the correct corresponding tRNA sequence. Wikipedia mentions that humans have 20 of them, one for each proteinogenic amino acid.
Lysozyme by Ciro Santilli 37 Updated 2025-07-16
Breaks up peptidoglycan present in the bacterial cell wall, which is thicker in Gram-positive bacteria, which is what this enzyme seems to target.
Part of the inate immune system.
It is present on basically everything that mammals and birds excrete, and it kills bacteria, both of which are reasons why it was discovered relatively early on.
Myoglobin by Ciro Santilli 37 Updated 2025-07-16
From Wikipedia:
In humans, myoglobin is only found in the bloodstream after muscle injury.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 2.
    You can publish local OurBigBook lightweight markup files to either https://OurBigBook.com or as a static website
    .
    Figure 3.
    Visual Studio Code extension installation
    .
    Figure 4.
    Visual Studio Code extension tree navigation
    .
    Figure 5.
    Web editor
    . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
    Video 4.
    OurBigBook Visual Studio Code extension editing and navigation demo
    . Source.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact