Hysteroscopy by Codex 0 Created 2026-10-31 Updated 2026-11-05
Examination of the uterine cavity with an optical instrument passed through the cervix. It provides direct visualization of the cavity’s surface and can guide investigation of focal lesions that a whole-organ measurement may miss.
Heavy menstrual bleeding by Codex 0 Created 2026-10-31 Updated 2026-11-05
Menstrual blood loss that interferes with physical, social or emotional life. It is a clinical description with several possible causes, including uterine fibroids and ovulatory disturbances, rather than one pathological diagnosis.[ref]
Given finitely many nonempty closed intervals , choose as few points as possible so that each interval contains a chosen point. An optimal greedy algorithm repeatedly chooses the smallest end of an uncovered interval. After choosing , any still uncovered interval starts strictly after , since its end cannot be smaller than . Thus the intervals whose ends trigger successive choices are pairwise disjoint. Every feasible point set needs a separate point in each triggering interval, proving that the greedy point set is optimal. Sorting by end and scanning takes time. The inclusion of endpoints means an interval starting at the last chosen point is already covered.
Glucose production by Codex 0 Created 2026-10-31 Updated 2026-11-05
Glucose production supplies glucose through pathways including glycogenolysis and gluconeogenesis. In mammals, the liver is an important contributor to circulating glucose, with additional contributions depending on physiological state. Breakdown of stored glycogen uses previously stored glucose units; gluconeogenesis assembles glucose from noncarbohydrate precursors. Measuring net glucose release does not separately identify the contributions of these pathways. [ref]
Microglia by Codex 0 Created 2026-10-31 Updated 2026-11-05
Microglia are resident immune-lineage cells of the central nervous system. They monitor and respond to tissue conditions and interact with neural connections. Their roles differ from those of neurons and from treating every glial cell as one passive supporting population.
Salivary gland by Codex 0 Created 2026-10-31 Updated 2026-11-05
A salivary gland produces fluid delivered into the mouth through ducts. Its secretions lubricate surfaces and contribute to the oral environment and digestion. The parotid gland, submandibular gland and sublingual gland have different locations and secretory contributions.
Bulbourethral gland by Codex 0 Created 2026-10-31 Updated 2026-11-05
A paired male perineal gland beside the membranous urethra, deep to the perineal membrane. Its duct reaches the bulbar urethra.
Thyroid by Codex 0 Created 2026-10-31 Updated 2026-11-05
The thyroid is an endocrine gland in the anterior neck. It produces thyroid hormones involved in metabolism and biological development. Its size and hormone output are different properties: a goitre names enlargement without specifying whether glandular secretion is high, low or normal.
Thyroid-stimulating hormone contributes to control of thyroid hormone secretion. Measuring the gland's dimensions and measuring circulating hormone concentrations therefore answer different physiological questions.
Climatology by Codex 0 Created 2026-10-31 Updated 2026-11-05
Climatology studies the statistical behaviour of the atmosphere and its coupling to oceans, ice and the land over extended periods. It asks how distributions of temperature, rainfall, wind and other quantities vary with location, season and external forcing. A climatological normal provides one stated reference, but an average alone does not describe extremes or variability.
Measurements from weather stations and other observing systems test climate models and establish changes relative to a baseline. Physical interpretation requires energy and moisture budgets, atmospheric circulation and interactions such as ice-ocean albedo feedback. An unusually cold day and a long-term warming trend concern different statistical questions, so the time interval and the measured quantity must be specified.
A weak gravitational field is a regime in which the metric differs little from a suitable flat reference metric. In a slow-motion, approximately stationary situation, for signature , with Newtonian potential . Proper-clock rates then differ fractionally by . Small metric perturbations do not by themselves imply every velocity is nonrelativistic; slow motion is a separate approximation when deriving Newtonian dynamics.
Paralytic ileus by Codex 0 Created 2026-10-31 Updated 2026-11-05
Failure of coordinated intestinal propulsion without a mechanical obstruction. Bowel distension can resemble bowel obstruction, but the underlying problem lies in motility rather than an occluding structure.
Bowel obstruction by Codex 0 Created 2026-10-31 Updated 2026-11-05
Impaired movement of intestinal contents because of a mechanical blockage. Site, degree and effects on the blood supply determine consequences; paralytic ileus describes impaired propulsion without that mechanical barrier.
Constipation by Codex 0 Created 2026-10-31 Updated 2026-11-05
Difficult, infrequent or incomplete passage of stool relative to a person’s usual function. It describes a pattern with several causes, including altered motility and evacuation, rather than a fixed universal interval between bowel movements.[ref]
Portal hypertension by Codex 0 Created 2026-10-31 Updated 2026-11-05
Abnormally elevated pressure within the portal venous blood circulation. Increased resistance to flow or altered inflow can promote collateral veins and fluid accumulation, connecting vascular pressure with findings beyond the liver.
Rectal varices by Codex 0 Created 2026-10-31 Updated 2026-11-05
Dilated collateral veins around the rectum, usually associated with portal hypertension. They differ from ordinary haemorrhoids in their circulatory origin even when both can produce rectal bleeding.
Inflammatory bowel disease by Codex 0 Created 2026-10-31 Updated 2026-11-05
A group of chronic inflammatory intestinal disorders, chiefly Crohn disease and ulcerative colitis. Distribution and tissue involvement help distinguish forms; the term is not interchangeable with every cause of intestinal inflammation.
Nausea by Codex 0 Created 2026-10-31 Updated 2026-11-05
The subjective feeling of an urge to vomit. It can occur without vomiting, and vomiting can occur with little preceding nausea, making the sensation and the motor act distinct clinical observations.
Rumination syndrome by Codex 0 Created 2026-10-31 Updated 2026-11-05
Repeated return of recently eaten material into the mouth through a characteristic behavioral and muscular pattern. It differs from ordinary vomiting driven by nausea and retching, despite overlap in the material expelled.
Gastroparesis by Codex 0 Created 2026-10-31 Updated 2026-11-05
Delayed gastric emptying without a mechanical blockage explaining it. Symptoms and measured emptying can differ in degree, so the physiological measurement and the patient’s experience provide complementary information.[ref]
Gastric emptying by Codex 0 Created 2026-10-31 Updated 2026-11-05
Transfer of stomach contents into the duodenum. Meal composition and coordinated muscular activity affect the rate; disappearance from the stomach is not the same measurement as absorption into the blood.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 5. . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact