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An affine open subscheme is an open subset of a scheme with its restricted structure sheaf, which is itself an affine scheme. Every scheme has an open cover by such subschemes. On an affine scheme, the principal open subschemes give an open basis.

On a Stein manifold $X$, every coherent analytic sheaf $\mathcal{F}$ has $H^q(X,\mathcal{F})=0$ for $q>0$. In particular this applies to the sheaf of holomorphic functions. If every nonempty finite intersection in an open cover is Stein, these vanishing results and the acyclic cover theorem compute the corresponding sheaf cohomology from its Čech cochain complex.

Let $f:X\to Y$ be a continuous map that is a closed map and whose fibres are compact. Then $f^{-1}(K)$ is compact for every compact set $K\subseteq Y$, without a Hausdorff hypothesis. Given an open cover, cover each fibre by a finite union $V_y$ of its members. The set $W_y=Y\setminus f(X\setminus V_y)$ is open, contains $y$, and has $f^{-1}(W_y)\subseteq V_y$. A finite subcover of $K$ by the $W_y$ uses only finitely many original cover members and covers $f^{-1}(K)$. Empty fibres cause no exception.

Only finite subsets are compact in the cocountable topology. An infinite subset contains distinct $c_1,c_2,\dots$. The open sets obtained by removing the tails $\{c_j:j\ge n\}$ form an increasing open cover, but every finite selection misses a tail point. Finite sets are compact in every topology.

A sheaf of modules over the sheaf of smooth functions is fine when every locally finite open cover admits a subordinate family of sheaf endomorphisms summing to the identity. Fine sheaves on a paracompact space are acyclic, so their positive-degree sheaf cohomology vanishes.

For a quasi-compact separated scheme and a global regular function $f$, global sections on $X_f$ are the localization of global sections by $f$. Choose a finite affine open cover. Its intersections are affine, so the sheaf gluing axiom describes global sections as the kernel of the difference map between two finite products of affine coordinate rings. Exactness of localization preserves this kernel, and localization commutes with those finite products. Localizing the same cover gives the claimed isomorphism. This applies before knowing whether $X$ itself is affine.

A topological space is paracompact when every open cover has a locally finite open refinement. Every metric space and every second-countable topological manifold is paracompact.