Inflation by Ciro Santilli 37 Updated 2025-07-16
Video 1.
One Million Dollars scene from Austin Powers
. Source.
Video 2.
100 Billion Dollars scene from Austin Powers
. Source.
ExplainingComputers by Ciro Santilli 37 Updated 2025-07-16
It is hard to say if this channel is good because of the awesome information, or if because of the absolute cutness of that British presenter. Maybe it is both.
NP-complete by Ciro Santilli 37 Updated 2025-07-16
A problem that is both NP and NP-hard.
This is the most plausible way of obtaining a full connectome looking from 2020 forward. Then you'd observe the slices with an electron microscope + appropriate Staining. Superintelligence by Nick Bostrom (2014) really opened Ciro Santilli's eyes to this possibility.
Once this is done for a human, it will be one of the greatest milestone of humanities, coparable perhaps to the Human Genome Project. BUt of course, privacy issues are incrediby pressing in this case, even more than in the human genome project, as we would essentially be able to read the brain of the person after their death.
As of 2022, the Drosophila connectome had been almost fully extracted.
This is also a possible path towards post-mortem brain reading.
Figure 1. Source. Unconfirmed, but looks like the type of frozen brain where a Microtome would be used.
Bisulfite sequencing by Ciro Santilli 37 Updated 2025-07-16
The main way to sequence DNA methylation. Converts methylated cytosine to uracil, and then we can sequence those.
Video 1.
Bisulfite Sequencing by Henrik's Lab (2020)
Source. Nothing much new that we don't understand from a single sentence in the animation. But hey, animations!
Analogous problem to the secondary structure of proteins. Likely a bit simpler due to the strong tendency for complementary pairs to bind.
Binds an amino acid to the correct corresponding tRNA sequence. Wikipedia mentions that humans have 20 of them, one for each proteinogenic amino acid.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
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