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Digoxin is a cardiac glycoside that inhibits sodium-potassium ATPase. The resulting changes in ion handling influence cardiac contraction and conduction. Blood concentration, tissue exposure and clinical response are related measurements with different time courses.[ref]
During this stage of the cardiac cycle, the ventricular inlet and outlet valves are both closed. Ventricular volume is fixed at its end-filling value , while increasing ventricular elastance raises pressure as . Arterial and venous pressures remain approximately fixed when the stage is short relative to their systemic resistance–compliance times.
Absence of detectable ventricular electrical activity in the assessed recording. It is one cardiac-arrest rhythm and differs from electrical activity that persists without effective pumping.
Gluconic acid is the carboxylic acid obtained by oxidizing the aldehyde end of glucose while retaining the rest of its six-carbon framework. Gluconic acid can form gluconate by loss of its acidic proton.
A keto acid contains both a ketone group and a carboxylic acid group. The position of the ketone relative to the acid group distinguishes α-keto acids, β-keto acids, and more remote arrangements.
Pyruvic acid and 2-Oxoglutarate are metabolically important examples of the α arrangement. Their carbonyl groups participate in transformations connecting carbohydrate metabolism with amino acid metabolism.
An alveolar capillary is a pulmonary capillary closely associated with the alveolar exchange surface. Its arrangement brings blood near air across a thin layered barrier. Effective gas exchange depends on matching local ventilation with perfusion as well as on barrier thickness.
The porous fuel-delivery component of a candle. Capillary action transports molten wax through its fibres to the region supplying gaseous fuel.
A malignant tumour with mesenchymal differentiation, including cancers of bone and soft tissues. It differs from epithelial carcinoma in cellular lineage rather than simply in anatomical depth.
A malignancy of plasma cells, often involving bone marrow and production of a clonal immunoglobulin or its components. Tissue injury and abnormal protein effects connect the cell population with systemic findings.
A cancer arising from melanocytes. Pigment production can vary, so a melanoma need not be visibly dark, and a dark lesion is not automatically melanoma.
A cancer of blood-forming cells, commonly involving bone marrow and blood. Abnormal cell populations can interfere with normal blood production without forming a single solid mass.[ref]
A tumour arising from germ-cell lineages, including testicular and ovarian forms. The cell of origin distinguishes it from tumors arising from supporting or surface tissues in the same organ.
A classification based on microscopic features associated with differentiation or proliferative behavior. It differs from tumour stage: a small localized cancer can still have high-grade cellular features.
Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 2. You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website.Figure 3. Visual Studio Code extension installation.Figure 5. . You can also edit articles on the Web editor without installing anything locally. Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension. - Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact





