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Researcher in organellar RNA regulation. Pfalz and collaborators investigated how site-specific binding of a pentatricopeptide repeat protein defines and stabilizes chloroplast transcript ends, connecting selective recognition with RNA persistence.[ref]
Researcher in chloroplast gene regulation. With Alice Barkan, Chotewutmontri investigated damage-triggered psbA messenger RNA translation, connecting protein synthesis with an assembly-linked autoregulatory circuit in photosystem repair.[ref]
Researcher in chloroplast signaling. Woodson and collaborators investigated sigma-factor-mediated retrograde signals controlling nuclear gene expression, connecting organelle state with regulation of genes located elsewhere in the cell.[ref]
Researcher in epigenetic inheritance. Ragunathan and collaborators experimentally separated inheritance of a chromatin state from sequence-specific recruitment, testing whether maintenance can persist after the initiating targeting signal changes.[ref]
Epigenetic inheritance uncoupled from sequence-specific recruitment by Kaushik Ragunathan and others. Title, author list and reported study
Researcher in cellular stress signaling. Inglis and collaborators investigated activation of GCN2 by the ribosomal P-stalk, connecting the translation machinery with a regulator that responds to amino acid availability.[ref]
Activation of GCN2 by the ribosomal P-stalk by Alison J. Inglis and others. Title, author list and reported study
Researcher in developmental RNA localization. With Kevin M. Forrest, Gavis investigated diffusion and entrapment of nanos messenger RNA in Drosophila, distinguishing selective retention from directed transport along an entire route.[ref]
Researcher in translational control. With Krishna M. Vattem, Wek investigated ATF4 regulation through translation reinitiation at upstream reading frames, connecting transcript architecture with a cellular stress response.[ref]
Researcher in chloroplast gene regulation. With Prakitchai Chotewutmontri, Barkan investigated how photosystem damage triggers psbA messenger RNA translation through an assembly-linked circuit, connecting protein production with repair demand.[ref]
Researcher in structural biology. Campbell and collaborators determined the structure of a bacterial RNA-polymerase sigma factor, connecting molecular architecture with selective promoter recognition.[ref]
Researcher in RNA processing. With Phillip A. Sharp, Moore reconstructed accurate cleavage and polyadenylation of an external RNA substrate, helping make transcript-end formation experimentally accessible.[ref]
Researcher in RNA processing. Zarkower and collaborators investigated the requirement for the AAUAAA signal sequence in transcript cleavage and polyadenylation, connecting a short RNA signal with formation of a mature transcript end.[ref]
Researcher in mitochondrial dynamics. Chen and collaborators investigated coordinated action of Mfn1 and Mfn2 in mitochondrial fission-fusion cycle, connecting organelle remodeling with embryonic development.[ref]
Researcher in anaerobic metabolism. With Miklós Müller, Lindmark described the hydrogenosome and its involvement in pyruvate metabolism, helping explain energy conversion in organisms with unusual cellular organization.[ref]
Researcher in reduced mitochondrial organelles. Tovar and collaborators investigated iron–sulfur protein maturation in Giardia organelles, connecting a mitochondrial remnant with a specialized cellular requirement.[ref]
Researcher in organelle biology. Mi-ichi and collaborators identified a sulfate-activation pathway in Entamoeba histolytica mitosomes, connecting a reduced organelle with a retained metabolic function.[ref]
Mitosomes in Entamoeba histolytica contain a sulfate activation pathway by Fumika Mi-ichi and others. Title, author list and reported study
Researcher in enzyme structural biology. Langan and collaborators used neutron and X-ray crystallography to investigate a conserved glutamate in beta-lactamase, connecting atomic positions with a proposed catalytic role.[ref]
Researcher in enzyme evolution. Orencia and collaborators combined directed evolution with structural analysis to investigate the emergence of antibiotic resistance, connecting sequence changes with altered enzyme behavior.[ref]
Researcher in RNA processing. With Claire L. Moore, Sharp investigated accurate cleavage and polyadenylation of an experimentally supplied RNA substrate, connecting sequence recognition with formation of a mature transcript end.[ref]
Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 2. You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website.
Figure 3. Visual Studio Code extension installation.
Figure 5. . You can also edit articles on the Web editor without installing anything locally. Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension. 
- Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact