The dependence of stretching force on extension of a molecule or polymer. Measurements with optical tweezers probe conformational entropy, stiffness and structural transitions.
Measurement and interpretation of cardiac electrical activity using body-surface electrodes. The resulting trace is an electrocardiogram; waveform timing reflects the coordinated activation and recovery of cardiac tissue.
A recording of time-varying electrical potential differences at the body surface due to cardiac electrical activity. Its QT interval spans ventricular depolarization and repolarization; a prolonged QT interval need not specify a unique underlying channel defect.
A disease in which altered ion channel number, transport or gating contributes to abnormal cell function. A causal account connects measured channel behavior to cellular activity, rather than inferring mechanism from a sequence variant alone.
A skeletal-muscle excitability disorder associated with variants of CLCN1, encoding the ClC-1 chloride channel. Reduced stabilizing resting conductance can permit repetitive action potentials and delayed relaxation after contraction.
A disorder characterized by delayed ventricular repolarization and susceptibility to dangerous cardiac rhythms. Different molecular subtypes affect different ion channels; type 3 can involve persistent inward sodium current caused by impaired fast ion-channel inactivation.
A compositionally enriched biomolecular assembly. Calling an assembly a condensate does not alone establish equilibrium liquid–liquid phase separation or a particular biological function.
A stress-associated RNA–protein assembly whose formation and composition depend on context. RNA enrichment does not establish obligatory translational silence.[ref]
Single-Molecule Imaging Reveals Translation of mRNAs Localized to Stress Granules by Daniel Mateju and others. Translation of granule-associated mRNAs
A researcher associated with statistical and biological physics, including robust perfect adaptation.
A researcher associated with quantitative studies of robust perfect adaptation in biochemical networks.
A physicist whose publications include the cold-atom Bloch oscillation experiment. His own publication list identifies the 1996 paper whose published byline uses Maxime Ben Dahan.
Publication list: www.phys.ens.fr/~dahan/Publications.html
Biophysicist whose research includes imaging of a membrane protein.[ref]
https://www.bioss.uni-freiburg.de/wp-content/uploads/CV_Ulbrich_2022.pdf. Primary identity record
Biophysicist whose research includes total internal reflection fluorescence microscopy.[ref]
https://lsa.umich.edu/biophysics/people/emeritus/daniel-axelrod.html. Primary identity record
Portrait of Suliana Manley
. EPFL; CC BY 4.0, via Wikimedia Commons. Source.Publication record: pubmed.ncbi.nlm.nih.gov/6334162/
Portrait of Max Delbrück
. Jonathan Delbruck, source and rights-releasing party named in the File; original photographer not separately established. Public-domain release by the party identified on Commons as author/copyright holder; worldwide fallback permission for any purpose; VRT ticket 2008120310001036., via Wikimedia Commons. Source.A biophysicist.[ref]
https://www.u-tokyo.ac.jp/focus/en/people/people000547.html. Independent biography: identity and specialization
A biophysicist.[ref]
https://www.phys.waseda.ac.jp/staff/kinoshita_kazuhiko/. Independent biography: identity and specialization
A biophysicist.[ref]
https://www.rubinsteinlab.org/lab-members. Independent institutional or self-authored biography: identity and specialization
A biophysicist.[ref]
https://www.rubinsteinlab.org/lab-members. Independent institutional or self-authored biography: identity and specialization
A biophysicist.[ref]
https://www.riken.jp/en/research/labs/chief/mol_physiol/. Independent institutional or self-authored biography: identity and specialization
Rikiya Watanabe. Portrait from the institutional profile.
A biophysicist.[ref]
https://med.virginia.edu/biophysics-program/biophysics-faculty/?facbio=1&id=1735735. Independent institutional or self-authored biography: identity and specialization
A molecular motor couples an energy supply to directed mechanical motion. ATP synthase provides a rotary example.
In inchworm motion the same head remains in front as the two heads advance without exchanging order. Ideal fixed label positions then advance by one centre-of-mass step per cycle, contrasting with the unequal alternating displacements possible in hand-over-hand motion of a two-headed motor.
In hand-over-hand motion, two attached heads exchange their leading and trailing roles. For a centre-of-mass advance , one head can move about while the other remains fixed. The motion of a fluorescent label also depends on its position on the motor.[ref]
Myosin V Walks Hand-Over-Hand: Single Fluorophore Imaging with 1.5-nm Localization by Ahmet Yildiz and others. Alternating light-chain label displacements support head exchange
A microtubule-associated molecular motor family. Many transport cargos toward plus ends, although direction and function vary among family members.
Articles by others on the same topic
Biophysics is an interdisciplinary field that applies the principles and methods of physics to understand biological systems. It combines concepts from biology, physics, chemistry, mathematics, and computational science to explore the physical mechanisms underlying biological processes. Key areas of study in biophysics include: 1. **Molecular Biophysics**: Examines the physical properties of biomolecules such as proteins, nucleic acids, and lipids.