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Cell biologist studying insertion of membrane proteins at the endoplasmic reticulum. Shao and Ramanujan S. Hegde analyzed how cellular machinery delivers and inserts hydrophobic proteins into a membrane.[ref]
Membrane Protein Insertion at the Endoplasmic Reticulum by Sichen Shao and Ramanujan S. Hegde. Title, author list and reported study
Cell biologist who, with Günter Blobel, used controlled digestion of nascent polypeptides to investigate their location in cellular fractions. Protection from digestion connected membrane enclosure with the path of protein synthesis.[ref]
Cell biologist studying protein targeting across membranes. With Bernhard Dobberstein, Blobel reconstructed aspects of cotranslational protein translocation, connecting information in a growing polypeptide with delivery to the secretory pathway.[ref]
Transfer of Proteins across Membranes I by Günter Blobel and Bernhard Dobberstein. Title, author list and reported study
Researcher in intracellular protein targeting. Laskey coauthored experiments identifying a nucleoplasmin region that directs nuclear import, connecting a part of a protein with transport through the nuclear pore complex.[ref]
Researcher in cytokinesis. Rappaport manipulated sand-dollar eggs to investigate the cleavage stimulus, using altered cellular geometry to test how division machinery determines the position of a furrow.[ref]
Experiments concerning the cleavage stimulus in sand dollar eggs by Raymond Rappaport. Title, author list and reported study
Researcher in membrane biology. With Larry Frye, Edidin studied rapid intermixing of surface antigens in fused cells, connecting the redistribution of labeled components with lateral mobility in the cell membrane.[ref]
Researcher in membrane biology. With Michael Edidin, Frye followed intermixing of mouse and human surface antigens after cell fusion, providing experimental evidence that membrane components can move laterally.[ref]
A cell biologist.[ref]
https://www.nobelprize.org/nomination/archive/show.php?id=12566. Nomination Archive: Camillo Golgi, 1843-1926, general pathology and histology; microscopic nervous-system research
Portrait of Camillo Golgi
. Portrait identified in the Wikimedia Commons file record. Source.Cell biologist whose work with James D. Jamieson traced transport of secretory proteins through pancreatic cells. Following newly synthesized material connected distinct cellular compartments into a functional secretory pathway.[ref]
A cell biologist whose joint work with George E. Palade traced the intracellular transport of secretory proteins.[ref]
https://magazine.alumni.ubc.ca/2019/spring-2019/departments/in-memoriam/james-d-jamieson. Institutional obituary: James D. Jamieson, 1934-2018, cell-biology research
Cell biologist and coauthor of an undergraduate teaching study introducing mammalian cell culture and viability measurements. The work connected direct observation of cultured cells with quantitative interpretation of cellular survival.[ref]
Portrait of Verónica A. Segarra
. External portrait linked by the institutional profile.A botanist whose name is associated with Brownian motion.[ref]
https://anbg.gov.au/biography/brown-robert.html. Australian National Herbarium, biographical notes: botanist, 1773–1858, and Keeper of the Botanical Department
Portrait of Robert Brown
. External public-domain lithographic portrait; Wikimedia Commons file record. Source.Researcher in ATP-synthase biophysics. Nakamoto coauthored experiments on temperature-dependent single-molecule rotation, connecting interactions between subunits with the catalytic dwell of the motor.[ref]
Researcher in molecular motors. Watanabe analyzed rotary catalysis of ATP synthase, connecting rotation, chemical steps and coupling between the enzyme’s membrane and soluble sectors.[ref]
Rotary catalysis of FoF1-ATP synthase by Rikiya Watanabe. Author list and described study
Rikiya Watanabe. Portrait from the institutional profile.
Researcher in structural biology. Rubinstein coauthored studies of bacterial ATP synthase, connecting cryo-electron microscopy structures with the mechanics and regulation of a rotary energy-converting complex.[ref]
Structure of a bacterial ATP synthase by Hui Guo and others. Author list and described study
Researcher in structural biology. Guo and collaborators determined bacterial ATP synthase structures, connecting subunit organization with the coupling of a rotary mechanism to ATP production.[ref]
Structure of a bacterial ATP synthase by Hui Guo and others. Author list and described study
Researcher in molecular biophysics and coauthor of direct observation of F1-ATPase rotation. The experiment connected ATP synthase activity with an observable rotary motion rather than an inferred mechanical analogy.[ref]
Direct observation of the rotation of F1-ATPase by Hiroyuki Noji and others. Author list and described study
Researcher in molecular motors. Noji and collaborators directly observed rotation of the F1 sector of ATP synthase, connecting enzymatic activity with mechanical motion at the single-molecule scale.[ref]
Direct observation of the rotation of F1-ATPase by Hiroyuki Noji and others. Author list and described study
Researcher in microbial genetics. With Salvador Luria, Delbrück analyzed variation in virus resistance among bacterial cultures, connecting fluctuations in resistant-cell numbers with mutations arising before selection.[ref]
Mutations of Bacteria from Virus Sensitivity to Virus Resistance by Salvador Luria and Max Delbrück. Author list and described study
Portrait of Max Delbrück
. Jonathan Delbruck, source and rights-releasing party named in the File; original photographer not separately established. Public-domain release by the party identified on Commons as author/copyright holder; worldwide fallback permission for any purpose; VRT ticket 2008120310001036., via Wikimedia Commons. Source.Masamitsu Futai coauthored single-molecule studies of F1-ATPase rotation. Measurements of catalytic dwell behaviour probe how interactions among subunits influence the chemical-mechanical cycle.
Changing temperature alters transition rates and can expose different rate-limiting processes. Such measurements link kinetic observations with the architecture of ATP synthase.[ref]
A biochemist.[ref]
https://www.osaka-u.ac.jp/en/news/topics/2012/03/201203013_1. Independent institutional or self-authored biography: identity and specialization
Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 2. You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website.
Figure 3. Visual Studio Code extension installation.
Figure 5. . You can also edit articles on the Web editor without installing anything locally. Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension. 
- Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact