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Assume steady fully developed laminar flow of a Newtonian fluid in a long circular tube, with no slip at a rigid wall. The Hagen-Poiseuille equation gives the volume flow ratewhere $R$ is the lumen radius, $\ell$ the tube length, $\eta$ the dynamic viscosity and $\Delta p$ the pressure drop. If $\Delta p$, $\ell$ and $\eta$ remain fixed, thenThus doubling the flow requiresThis estimate neglects pulsation, arterial compliance, entrance losses, the detailed shape of a stenosis and changes in the rest of the circulatory resistance. It treats blood as a homogeneous Newtonian fluid and assumes that enlarging the artery does not change its applied pressure drop. These assumptions supply the intended fourth-power scaling; an actual circulation need not keep that pressure drop fixed.