Ciro Santilli @cirosantilli 34

This is one of Ciro Santilli's most important principles.

Steve Jobs has a great quote about this. He's totally right on this one!

Decide your goal first, and then do whatever is needed to how to reach it.

Don't start randomly learning tech, because that means you will waste a lot of time learning useless stuff.

There is of course some level chicken-and-egg paradox in this, as highlighted by Dilbert, since choosing an achievable goal in the first place requires some level of technical understanding.

However, it is much more common that people will get way too involved in learning useless stuff and lose sight of the useful end goals.

Rather, take an iterative approach:

There is some truth to the counter argument that "but if you don't spend a lot of time learning the basics, you can never find solutions".

However, these people underestimate your brain. The brain is beautiful, and human intuition is capable of generating interest towards the things that are actually useful to reach your goal. When you feel like learning something related to your goal, by all means, give yourself the time to do so. But this still be much more efficient than just learning random things that other people tell you to learn.

Bibliography:

Main article: Section "Brain-computer interface".

This is one of the deep tech bets that Ciro Santilli would put his money in as of 2020.

How hard could it be? You just have to learn the encoding of the neural spine/eyes/ear, add an invasive device that multiplexes it, and then the benefits could be mind blowing.

Musk approves.

Interestingly and obviously, the initial advances in the area are happening for people that have hearing or vision difficulties. Since they already have a deficient sense, you don't lose that much by a failed attempt.

Hearing is likely to be the first since it feels the simplest. Ciro heard there are even already clinical applications there. TODO source.

At first, Ciro Santilli was just cycling to work with an extremely shitty bike he bought on a second hand shop. He knew nothing about bicycles, and the seat was way, way too low, the seller should be prosecuted for selling that to him. Ciro later understood that this was even a woman's bicycle with a low top tube! That's what you get for being so cheap.

But then at some point he bought another slightly less cheap touring bicycle, but this time from a much more trustworthy source: a colleague who was leaving the company and moving out, and this one was actually reasonable. It was the right size to start with!!! And so at some point, out of boredom, Ciro started to adventure out of town on weekends to neighbouring villages, and it just felt so good.

Ciro had started by taking his laptop-computer on his backpack, and stopping at a cafe on some nearby town where he would do some coding over the weekends. Especially during winter, drinking tea with a cake as a break during bicycle ride was the best thing ever. In one place, there was even an electric heater that you could sit in front of. But at some point, those rides start being too short, and you start doing longer real rides without your computer. And since those take more time, you generally don't feel like staying on a far place for a very long time. So you end up creating the "real ride" category and "a small ride to get somewhere nice to code" category clearly split.

He had had the "cyclists high" version of "runner's high". A light euphoria in your head, or a pulsating feeling of pleasure in your legs and lower torso. This reminded Ciro of:except that it is not as intense, and does not destroy your life.

Like other drugs:

Cycling just gives you an amazing sense of freedom! Ciro likes to imagine himself as a migratory duck when he is riding his bike on cold or wet days.

The prospect of being able to reach nice new places keeps the experience fresh for a very long time.

Ciro likes to decide location on a whim on the day prior. He checks the wind to try and ride parallel to it, and then let's his mind wonder, until an image comes up, some some nice place Ciro was to once. And so the next day, he goes in that general direction again.

Each time you try to find a new cool location, and sometimes you just stumble into amazing stuff without knowing about it. Ciro likes to keep open to new experiences. Keep your eyes open, and if something looks curious, just check it out! Talking to locals for tips is also a great way to find new stuff.

One thing that Ciro often feels is rather excited on the way out, and lightly afraid of going futher at each step because of the return. And during the return, there is a greater feeling of worry and resignation, as you are more tired, you've seen what you wanted to, and you just have to get yourself homehow, often going back through paths that you know better. This reminds Ciro of the ending of the film In the Realm of the Senses (1976), in which the sex obsessed couple plays a strangling sex game, and the man says that it hurts too much when she stops strangling him, and so she strangles him to death. She also cut his penis and carried it around in a bag afterwards, but that not relevant to the cycling analogy.

It is funny, but sometimes this gives Ciro the same feeling that he had as a child playing 2D exploration RPGs such Pokemon and Final Fantasy VI as you explore the wild: Ciro can often hear the FF VI overworld soundtrack, or imagine that a Charmeleon is hidden just around the corner of this new towns he's never been to before. Because in the places you live and have walked a million times, you know there is no magic. But in a new place that you're visiting for the first time? Anything is possible there.

The main difference from video games is that the real world is much much more detailed and diverse, and the freedom is much more real. Also you can't just walk into any house or field like in the games, and there are more empty or repetitive areas that can sometimes get boring since they weren't hand designed. And if you die on a car crash there are no continues.

Another type of game that comes to mind are survival games and roguelikes, where it feels amazing to learn things that actually mean the difference between life and death, and conquering the environment. But also permadeath.

It also gives Ciro the magic feeling of awe that he had as a child when walking around his beloved hometown of Santos, São Paulo, Brazil in the sunshine. And sometimes the feeling of excitement that he had as a child before getting gifts for Christmas. Ciro then once watched a YouTube video where ex-heroin addicts describe the feeling of taking heroin (orally, TODO can't find the video anymore, I think it was this guy) exactly like that: the anticipation of getting Christmas gifts, and he instantly understood.

Ciro also likes to pick random gravel from time to time. He believes that his style of route choice reflects Ciro Santilli's self perceived creative personality: Ciro likes to go where few other people go. And he only needs to go there once to be satisfied, not master and speedrun it afterwards.

Ciro avoids riding at night of course. But when it happens and you are prepared with the safety lights and the route knowledge, it makes for some of the most memorable rides of your life.

As you start cycling, you can feel the endorphins levels rise little by little, and your mind go deeper and deeper into slumber, getting close and closer to the ground, until you reach a point where you feel like you are part of the road. Trainspotting (1996)'s overdose scene comes to mind: www.youtube.com/watch?t=66&v=_IDJpB9de3E

It is amazing how you feel much less cold and hunger when cycling, to the point of being dangerous: always carry some chocolate bars in case you hit the wall! This is especially true at the beginning of the addiction, but with increased drug tolerance and knowledge/awareness/preparation, this starts to feel more normal.

As a friend of Ciro once said: you start to become like a wolf, who knows every cyclable little road in a 30km radius around your home.

As of 2020, Ciro is at that "should I buy a more reasonable road bike" moment. Let's see how it goes. If he does, cycling trips with the bike on a plane are likely.

As a software engineer, trying to repair a mechanical system like his bike reminds Ciro very strongly of how the physical engineering is brutal. Millimetric changes can make huge differences, it is mind blowing! Good lesson to have in mind.

Another thought that often comes to Ciro's mind is that bicycles are not regular possessions because they break a lot. Rather, they must be seen as a kind of transportation tax that you have to pay to feel amazing riding them rather than feel crappy riding a bus or train.

One interesting feeling that Ciro gets from cycling is that it is an intermediate between walking and riding a car. Ciro felt this especially strongly when he lived near work, at a distance that you could either walk or cycle. When you walk, you can just see so much more of the surroundings, it is astonishing. When you cycle, you just go much faster, and you attention is much more towards the front, so you feel surroundings much less. On the other side, cycling allows you to feel different things. E.g. in wider open areas, there isn't much detail to see anyway, so you can better feel those areas on the faster speed of the bike. A similar feeling applies to how pedestrians feel like flies when you are on a bike, just like you must feel like a fly to car drivers. Ciro later learnt that a person of similar literary ability to his, Ernest Hemingway, had a famous related similar quote:

Although Ciro does not run because of his itchy legs issue, he finds it interest to contrast cycling with running, notably:So maybe the ultimate sport would be to cycle to a good cross-country running location and then run over there?

Ciro's natural work-time rhythm as of 2020 in his shitty Kross bicycle (2017) was a 60/70km ride every 3 days. Or a 35/40km ride every 2 days. Or one longer 100/120km ride every 4 days. Less than 35km does not count as a ride. His average speed on anything above 70km and relatively flat is always 20km. Always. Ciro once read that that one hunt every three days was a common Paleolithic practice. Cycling is obviously a substitute for hunting. Perhaps the imminent danger of being crashed by a car at all times also has the positive side of playing the "danger" part of the hunt: Video "Why football is the most popular sport in the world by Desmond Morris"

Apocryphally attributed to H. G. Wells as per Quote Investigator quoteinvestigator.com/2022/12/10/bicycle-hope/:

Restrict the fuck out of cars.

The "most prestigious French engineering school". Only 3 Nobels though as of 2019, the scientists are mostly at École normale supérieure (Paris). A gazillion CEOs ad politicians however.

Ciro Santilli studied there from 2010 to 2013.

Ciro considers him entering at Polytechnique a small miracle. First, on his second year of University in Brazil, he first had to fail to join the also good but not as good École centrales, which really annoyed him as he saw the "other good students" who wanted to go out get their wish. This also explains why there are so few students from his university going to Polytechnique in the late 2010's: most already went to other locations! Then, on his third year, he tried Polytechnique and got in despite feeling that the others who got in knew much more mathematics and physics than him. Rather, Ciro believes that he got in chiefly due to his intense passion for the sciences which he showed during the interview.

The miracle would have been even greater if it had happened in 2020. At this time, out of 10 Brazilians, 9 are from ITA, the "hardest to get into" university in Brazil, and also military like Polytechnique. Make no mistake, those students are amazing and deserve it without any doubt. But there is more to the story. It could be argued that many of them only go because they don't have any other choice of exchange program. Remember: Ciro had to fail applications on previous universities before getting into Polytech. Also, they don't get any Brazilian degree because ITA has no agreements with Polytechnique, and are therefore extremely likely to never come back. Not that Ciro thinks this is particularly bad for Brazil though, but it does make for a better deal for France overall as well. They also happen to have closer ties across cohorts of different years, and have managed to maintain a Google Doc with scanned past examinations (as of 2020 however, some/all of those examinations have been uploaded publicly, big kudos to them). Also almost all of them are software engineers, which is one of the few disciplines given at the relatively small ITA. This lack of diversity might not be ideal: if I were France, I would rather fish around all top Brazilian schools for "the best".

Besides the amazing funding/opportunities/alumni/staff loop which you can read about elsewhere, Polytechnique is amazing because you can choose what you will study every year to a very large extent.

This is in huge contrast to the crappy systems Ciro had seen e.g. in Brazil's Polytechnic School of the University of São Paulo, where students have to decide basically all their courses in huge packages, either at university entry (thus when they are completely clueless), or at a single point inside the university studies, changes being much harder.

Life quality was also amazing. Good free accommodation on campus and at the time a no-obligations scholarship for every foreign student great sport facilities. It seems that after Ciro left however more restrictions are added to the scholarships, what a shame! As of 2020 not everyone gets scholarships anymore it seems, mostly only loans that have to be paid back later. And those who are not poor have to pay Polytechnique scholarship fees on top of their living costs. And thus French austerity measures are undermining the greatest long term investment a country can possibly make: that of importing the very best students from other countries into yours. This after their host country has already spent 20 years raising and selecting them. And you won't even pay them 2 years of frugal existence to steal some of them them. Even if those students move away from your country later on, the contacts they made in your country mean they are much more likely to bring businesses over. But some will stay. Basically, France is becoming more like the United States.

This also makes it much more difficult for those students to do a PhD afterwards, where they would get paid very little, and are unable to pay their student debts. A PhD would be where they would possibly bring more of the next big thing to your country. Instead, they are much more likely to just go work for some big American company data wrangling and bring nothing to your country but their student debt dividends instead, which they will be pay to pay for in one year with those amazing salaries. And unsurprisingly many go to into banks. What a big time fail, France.

Sport was mandatory due to the military nature of the school. This did have the upside of getting students together more, although Ciro is against all forms of forced intellectual of physical activities for students. If you liked your sport it would be really cool though. But due to Section "Ciro Santilli's knee", he was forced to give up his first beloved choice which was soccer... life can be cruel. If only Ciro had known cycling at at the time, and if only that had been one of the sports you could choose (but of course it isn't, no school will want the bad reputation of when one of their students gets killed in a car accident).

There were also some useless "military exercises", or special situations in which you had to wear the useless school uniform as a formal "respect social clothing". Ciro Santilli is completely against all that meaningless bullshit, this his just a form of theatrical masturbation to nostalgically remember the good old days of Napoleon when France still ruled the world, and before they tortured the Algerians, see also: Video 4. "Gérard Fuchs interview from Ils racontent la Guerre d'Algérie (1982)". If you are going to do military-like stuff, then at least teach students how to shoot modern rifles and modern warfare tactics (which some of the French students actually do in the pre-school mandatory internship), and not this 18th century bullshit. Ciro favours of course the hoodie-wearing, "I only care about your abilities meritocracy" culture of Silicon Valley. And without the political correctness now associated with it in the 2020s. And no shooting people if possible.

During the time Ciro was at Polytechnique in early 2010's, the school was really isolated in the Plateau de Saclay, there were no shops in 10 minute walking distance! You either had to climb 300 steps to go down to the nearest village, Lozère, or take a bus to the nearest town, Massy. The fact that Times Higher Education ranked it as the second best university in the world in 2019 (archive) makes it good justice, given the small 500 student body. Things started to change a bit after Ciro left however, with the creation of the Polytechnic Institute of Paris, which is bringing other schools to the Lozere area. This is for the best, as it might improve the global rankings of Polytechnique. Also it is a waste to have so few students at a technopole. But it will reduce the mystique of the place. You can't have everything in life.

Before 1976, Polytechnique was actually in the center of Paris at the Latin Quarter, so the Lozère mystique is not a traditional thing. But even when in Paris, students were in theory restricted to school grounds a most of the time. Although there are famous stories of a certain tree that could be used to climb the fence to go to Parisian parties when they couldn't stand it anymore. The tree was somewhat intentionally overlooked by school administrators. Polytechnique was drawn to Saclay no doubt because of the gravity of the CEA Paris-Saclay, France's analog to the United States Department of Energy national laboratories.

This made for some good memories though. The isolation favored concentration, and gave the place a mystical feeling. And then when you went to eat amazing Chinese food in Paris it just felt even more special and magic since you were so limited during the week. It was also under those magical circumstances in which Ciro met his wife, another student of the school, see also: Section "The main function of university is sexual selection".

Ciro also agonized about passing courses to get useless grades though! Polytechnique is hard for most Brazilians, specially if you select the more mathematics oriented courses, because the French students were math brainwashed for two years before joining.

Ciro's favorite spots/activities:

The following promotional videos give an idea of how the school looks like, although they fundamentally miss the little corners that Ciro really loved in that the place and which made it magic:

And a one second Ciro Santilli appearance from a 2016 video made during the annual Brazilian barbecue (or as close as you an get to it) which many ex-Brazilian students attend able: www.youtube.com/watch?v=ndX_-A2Rjpo&t=189 wearing a Ring t-shirt.

Startup lists:

Deep tech (have labs) unicorns:

Almost deep tech but possibly without labs:

This is the most important of all points.

Don't set goals for your students.

Ask students what they want to do, and help them achieve that goal.

If they don't know what to do, give suggestions of interesting things they could do.

Once they have a goal, just help them learn everything that is needed to achieve that goal

If they don't have a goal, any attempt to learn is a total and complete waste of time.

This is because the universe of potentially useful things that can be learnt is infinite, and no human can ever learn everything.

The only solution, is to try and learn only what seems necessary to reach your goal, and just try to reach your goal instead.

This approach is called backward design.

Also, setting overly ambitious goals, is a good idea: the side effects of ambitious goals are often the most valuable thing achieved.

"Graduating" and "getting a diploma" are not valid goals, because they are useless. A goal has to be either an amazing specific technological or artistic development.

See also: github.com/cirosantilli/awesome-whole-cell-simulation

As of 2019, the silicon industry is ending, and molecular biology technology is one of the most promising and growing field of engineering.

Such advances could one day lead to both biological super-AGI and immortality.

Ciro Santilli is especially excited about DNA-related technologies, because DNA is the centerpiece of biology, and it is programmable.

First, during the 2000's, the cost of DNA sequencing fell to about 1000 USD per genome in the end of the 2010's: Figure 2. "Cost per genome vs Moore's law from 2000 to 2019", largely due to "Illumina's" technology.

The medical consequences of this revolution are still trickling down towards medical applications of 2019, inevitably, but somewhat slowly due to tight privacy control of medical records.

Ciro Santilli predicts that when the 100 dollar mark is reached, every person of the First world will have their genome sequenced, and then medical applications will be closer at hand than ever.

But even 100 dollars is not enough. Sequencing power is like computing power: humankind can never have enough. Sequencing is not a one per person thing. For example, as of 2019 tumors are already being sequenced to help understand and treat them, and scientists/doctors will sequence as many tumor cells as budget allows.

Then, in the 2010's, CRISPR/Cas9 gene editing started opening up the way to actually modifying the genome that we could now see through sequencing.

What's next?

Ciro believes that the next step in the revolution could be could be: de novo DNA synthesis.

This technology could be the key to the one of the ultimate dream of biologists: cheap programmable biology with push-button organism bootstrap!

Just imagine this: at the comfort of your own garage, you take some model organism of interest, maybe start humble with Escherichia coli. Then you modify its DNA to your liking, and upload it to a 3D printer sized machine on your workbench, which automatically synthesizes the DNA, and injects into a bootstrapped cell.

You then make experiments to check if the modified cell achieves your desired new properties, e.g. production of some protein, and if not reiterate, just like a software engineer.

Of course, even if we were able to do the bootstrap, the debugging process then becomes key, as visibility is the key limitation of biology, maybe we need other cheap technologies to come in at that point.

This a place point we see the beauty of evolution the brightest: evolution does not require observability. But it also implies that if your changes to the organism make it less fit, then your mutation will also likely be lost. This has to be one of the considerations done when designing your organism.

Other cool topic include:

It's weird, cells feel a lot like embedded systems: small, complex, hard to observe, and profound.

Ciro is sad that by the time he dies, humanity won't have understood the human brain, maybe not even a measly Escherichia coli... Heck, even key molecular biology events are not yet fully understood, see e.g. transcription regulation.

One of the most exciting aspects of molecular biology technologies is their relatively low entry cost, compared for example to other areas such as fusion energy and quantum computing.

As of 2020, Ciro Santilli is getting excited about quantum computing, which is a deep tech field.

He's a bit lazy to explain why here, but Googling will be more than enough.

There is a risk it will fizzle and the bubble pop, like any revolution.

But recent developments are making it too exciting to ignore.

Quantum mechanics is quite a broad term. Perhaps it is best to start approaching it from the division into:

Key experiments that could not work without quantum mechanics: Section "Quantum mechanics experiment".

Mathematics: there are a few models of increasing precision which could all be called "quantum mechanics":

Ciro Santilli feels that the largest technological revolutions since the 1950's have been quantum related, and will continue to be for a while, from deeper understanding of chemistry and materials to quantum computing, understanding and controlling quantum systems is where the most interesting frontier of technology lies.

So that he can work full time on OurBigBook.com and revolutionize advanced university-level science, technology, engineering, and mathematics eduction for all ages.

Donating to Ciro is the most effective donation per dollar that you can make to:

Ciro's goal in life is to help kids as young as possible to reach, and the push, the frontiers of natural sciences human knowledge, linking it to applications that might be the the next big thing as early as possible. Because nothing is more motivating to students than that feeling of:rather than repeating the same crap that everyone is already learning.

To do this, Ciro wants to work in parallel both on:

Ciro believes that this rare combination of both:produces a virtuous circle, because Ciro:

As explained at OurBigBook.com and high flying bird scientist, Ciro is most excited to make contributions at the "missing middle level of specialization" that lies around later undergrad and lower grad education:But on that middle sweet spot, Ciro believes that something can be done, in such as way that delivers:in a way that is:

Ciro believes that today's society just keep saying over and over: "STEM is good", "STEM is good", "STEM is good" as a religious mantra, but fails miserably at providing free learning material and interaction opportunities for people to actually learn it at a deep enough level to truly appreciate why "STEM is good". This is what he wants to fix.

The following quote is ripped from Gwern Branwen's Patreon page, and it perfectly synthesizes how Ciro feels as well:

In addition to all of this, financial support also helps Ciro continue his general community support activities:

If you are going to live, you might as well chase one of them.

You might not achieve them in your lifetime, but you never know. At some point, the pieces just "fall into place", and they happen.

And they will all come from deep tech.

Ciro Santilli would like to contribute to them. but this is a bit less realistic than software projects.

But who knows? Maybe he can code some stuff in those areas.

And one can at least have some fun by learning deeply about those subjects.

Ciro Santilli approves of this one, related: Section "Free gifted education".

The downside of the Thiel Fellowship is that it is realistically impossible for its fellows to do anything in deep tech, only information science startups would be possible, as they would not have the labs, or lab skills required for any deep tech if they drop out before a PhD. Related: Section "The only reason for universities to exist should be the laboratories".

The only solution is the harder process of actually remodelling our very broken educational system.

Like all poor countries, Brazil's lack of money and scientific culture severely limit its ability to make technological and scientific advances.

While this sounds obvious, Ciro Santilli has felt it first hand since he moved from Brazil to Europe, and it is just shocking.

In the city of Santos for example, despite being a dream place from the natural point of view, it would be completely impossible to achieve any deep tech technical advance that impacts the world. In Europe however, there are several several places where this can happen.

Many of the student exchange programs Ciro witnessed in the 2010's in Brazil were inefficient because they were requiring students to come back immediately after university or PhD in fear that those students will never come back.

This is useless, because you don't learn anything unique during university: the truly valuable knowledge is obtained when you work for several years as a postdoc in a world class research laboratory or as an engineer in a world class company.

Therefore, Brazil should learn from the Chinese exchange system, which lets students go do whatever they want, and once they are Gods of the domain, entices them back with great positions and pay as heads of laboratory back in China. Just don't do fraudulent stuff like this like China did, or else you will get a bad rep.

To help this university collaboration happen, we should create communication channels between exchange students and professors of the origin country who work on the same domain so that they can discuss the subject. For example, once Ciro Santilli wanted to contact some of his former teachers at the University of São Paulo about "advanced" topics he had been exposed to as part of his job. However, they didn't even reply to his email, and Ciro didn't know who else to contact. This must never happen. We need a way to informally contact several professors of a given domain informally, to increase the chances that at least one might be interested. It is pointless to just let students loose abroad and hope that they will bring things back to their home country: a more cohesive infrastructure is needed to nurture that.

There is basically one sane way to achieve these goals: the exchange programs must be organized at a national level, not in an ad-hoc per-university manner.

Another good idea is to have taxes that depend on your nationality alone and which only start collecting when you reach a very high amount of net worth. So e.g. if someone leaves the country and makes it big, then and only then does the Government starts clawing back the benefits of its investments in the person. Furthermore, such taxes could be reduced if the person brings some of the business back to the country. And mandatory taxes should be charged if the person decides to drop their nationality at some point.

The above points would also be greatly eased by having a national-level exchange program. E.g. in Brazil in the 2010's which Ciro experience, every university had different terms and conditions, which made everything a mess. Exchange programs must be treated as a unified federal policy.

Ciro actually had to return for just six months from the École Polytechnique to the University of São Paulo, to finish a course he had only done the generic Maths/Physics introduction to. Students from other Brazilian universities were forced to return for up to 3 years even to get their Brazilian diplomas! Ciro was lucky that his teachers understood the situation, and allowed him to develop online learning projects instead of his supposed control engineering projects, which hopefully will have led to changing the world with motivation one day. And for this, Ciro is eternally thankful.

This shows the complete and total lack of any Brazilian strategy to send its students abroad to really learn valuable things and then come back. There is no strategy at all. Things have just reached an equilibrium point of bureaucracies, Brazilian universities trying to bring students back to validate useless diploma pieces of paper, and foreign universities no caring about that, and just wanting the students to say abroad forever.

Ciro was once talking about why so few Brazilians go study abroad compared to the Chinese. Besides the likely true "there are a lot of Chinese" argument, his wife made another: good point Brazil is not so bad to live in, because you have good food and freedom, while China only has good food.

But Ciro still fells bad that so few of his University of São Paulo colleagues, who learnt automation and control engineering, are doing deep tech. Nor physical engineering. They have all basically become computer people like Ciro.

This is not their fault. They basically don't have a choice: all physical science and technology is done in rich countries.

Yes, someone has to implement the newest tech to improve local country efficiency in projects that will never spread abroad.

But who will be left then for the next big thing problems that would really make Brazil richer? 6 out of 30 person class ended up working on a gaming company at one point, even though they were not crazy passionate about the field! What could possibly be a worst investment for society?

This lack of technological innovation can also be clearly seen when you research investment options available in Brazil. Huge emphasis is put on fixed return financial products (often inflation adjusted) linked to base non-tech business such as housing market and agriculture. And when you look to the returns of the stock market on s&P 500-analogue backed exchange-traded funds, they do not seem obviously better, especially considering inflation and taxation benefits that exist for some of the other investment possibilities.

When the companies of a country are not clearly the best investment, you know that something is wrong. They are highly specialized money making machines, remember! And housing and agriculture are not such innovative markets where people can hugely influence efficiency.

When it is best to send students is a good question. Undergrad studies could be easily reproduced in poor countries if they had any intelligence at all, since even in rich countries laboratory usage is always limited. Masters and PhD are generally more valuable moments to send people out. The question is if the students will actually have a fighting chance without having been out, in particular in terms of language skills. Ciro feels that Masters are a good focus point for entry, as that is where PhD links are more actively done.

Poor countries don't have a lot of money.

Therefore, you have to pick a few key the next big thing deep tech bets, and invest on those enough.

These have to be few, because your country is poor, and so you can't invest on everything.

Therefore, the bets have to be well selected, because it is useless to make several insufficient investments: you have to pick a few ones, and put enough time and money into each one of them for them to stand any chance. These bets should be made and reevaluated on 5/10 year horizons.

The key things that you have to select are:

And then you only tax those companies heavily when the start to bring in real money. These are startups remember! You only need 5 unicorns a year to call it a success. And countries should not be greedy and invest through equity, but rather recoup their investment through taxation alone.

Ciro's second removed uncle, who was a physicist at the University of Campinas, one of the best universities in the country, told him an anecdote. He had moved from fusion energy research to solar cell research. At some point, there was a research lab that needed 10 million to buy a machinery critical for their experiment. They asked and asked, and finally the government gave them only 2 million. So in the end they spent those 2 million in random ways, but of course did not achieve their research goal and no money came out of it.

He also explained how as a result of the insufficient investments, he felt clearly that some of the semiconductor production facilities related to solar power he saw simply were not able to control the production process adequately to produce consistent silicon. As a result, everything failed sooner or later as people found more and more bugs that they did not have the time to solve.

Another key investment is enticing back experienced exchange-students who have learnt new techniques to be heads of laboratory/founders to back in your country.

A fantastic initiative from Brazil for example is BRASA, which aims to put together Brazilian exchange students to make a difference back in Brazil.

Do not try to forbid external companies from selling in your country. Instead, fund your own companies to be able to fight the external market off. And if they can't, let them die and pick a different bet. Video "How Taiwan Created TSMC by Asianometry (2020)" has a good mention. Protectionism is something that Brazil notably tried to do, and look at what it led, not a single international success.

You can always learn pure theory later on for free or very cheap from books.

And above all, you can always learn software engineering later on for free, because the programming community is so much more open than any other so far, notably e.g. with Stack Overflow and GitHub, see also: Section "Ciro Santilli's Open Source Enlightenment". Ciro Santilli is trying to change that with OurBigBook.com, but don't hold your breath. But it is increasingly hard to understand why there isn't an university that forces teachers to publish all their notes and lecture videos (which should be mandatorily recorded) with a Creative Commons License, and then let anyone take whichever exams they want for a small fee or for free.

Actually, there is a good chance you will learn to program, like it or not, because chances are that you won't be able to find as decent a job doing anything else.

But there is one thing you cannot learn for free: laboratory work. Laboratory work is just too expensive to carry out outside of an institution.

Basically, if you don't do laboratory work in undergrad, you will very likely never be able to do so in your entire life.

Because laboratories are so rare and expensive, it is laboratories that put you in the best most unfair position at creating world changing deep tech startups, which is why when in doubt, choose the course that has the most experimental work. Yes, you won't be able to achieve those insanely concentrated equities of the early-Internet, as you will need more venture capital to run your company, but those days are over now, deal with it.